PMC:7556165 / 70534-70942 13 Projects
Annnotations
Id | Subject | Object | Predicate | Lexical cue |
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T419 | 0-408 | Sentence | denotes | The administration of a large amount of soluble form of ACE2 could represent an intriguing opportunity, since excessive ACE2 may exert dual functions: (a) competitively bind SARS-CoV-2 to neutralize the virus and/or slow viral entry in the host cell; (b) rescue cellular ACE2 activity, which negatively regulates RAAS and may theoretically exert a protective effect in lung injury (Verdecchia et al., 2020a). |