| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T276 |
0-147 |
Sentence |
denotes |
Since SARS-CoV-2 and SARS-CoV share the same host cell receptor, it was early questioned whether SARS-CoV-2 retains the same RBD motif of SARS-CoV. |
| T277 |
148-224 |
Sentence |
denotes |
SARS-CoV RBD corresponds to residues 306–527 of S protein (Li et al., 2005). |
| T278 |
225-364 |
Sentence |
denotes |
Sequence analysis shows that residues 319–541 of SARS-CoV-2 (S319–341) share 73.9% sequence identity with SARS-CoV RBD (Wang et al., 2020). |
| T279 |
365-495 |
Sentence |
denotes |
Accordingly, Wang et al. (2020) clearly demonstrated that S319–341 corresponds to SARS-CoV-2 RBD by immunofluorescence microscopy. |
| T280 |
496-699 |
Sentence |
denotes |
Indeed SARS-CoV-2 S1 and S319–341 positively colocalized with GFP-tagged ACE2 expressed on cell surface of HEK cells, whereas this interaction did not occur with membrane-expressed hDPP4 (MERS receptor). |
| T281 |
700-829 |
Sentence |
denotes |
Additionally, soluble ACE2 inhibited the interaction between viral proteins and ACE2-expressing cells in a dose-dependent manner. |
