Id |
Subject |
Object |
Predicate |
Lexical cue |
T193 |
0-221 |
Sentence |
denotes |
ARDS is an overly aggressive form of ALI and it is the final mechanism of lung injury in many diseases, including sepsis, acid aspiration, pancreatitis, anthrax and virus infections (Spanish flu, H5N1 avian flu and SARS). |
T194 |
222-367 |
Sentence |
denotes |
Imai et al. developed three ACE2 knockout mice models with severe ARDS induced by acid aspiration, endotoxin administration or peritoneal sepsis. |
T195 |
368-589 |
Sentence |
denotes |
They showed that ARDS was accompanied by increased vessel permeability, lung oedema, and infiltration of inflammation cells, with consequent impairment of respiratory function (Imai et al., 2005, 2007; Kuba et al., 2006). |
T196 |
590-734 |
Sentence |
denotes |
The phenotype was dramatically improved and rescued either administering ACE2 recombinant analogs or AT1Ra inhibitors (Imai et al., 2005, 2008). |