PMC:7555630 / 13887-15690 JSONTXT 8 Projects

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Id Subject Object Predicate Lexical cue
T86 0-263 Sentence denotes Similar to the observations in patients who developed COVID-19 in the general population, our cohort was predominantly male (64%), 60 years of age or older (89%), had high-risk comorbidities for COVID-19 (78%), and most resided at an extended care facility (64%).
T87 264-348 Sentence denotes Of note, twenty-one (58%) of the patients in this cohort also had comorbid dementia.
T88 349-630 Sentence denotes A recent retrospective study of 627 subjects admitted to an acute hospital in northern Italy yielded 82 patients (13%) who carried a prior diagnosis of dementia, but with a staggering 62% mortality rate, as compared to 26% in patients without dementia at the same institution [16].
T89 631-713 Sentence denotes Of the thirteen patients in our cohort who died, nine (69%) had comorbid dementia.
T90 714-799 Sentence denotes The overall mortality rate in our cohort for patients with comorbid dementia was 43%.
T91 800-902 Sentence denotes This was higher than the mortality rate of patients with a parkinsonism in this cohort, which was 37%.
T92 903-1118 Sentence denotes In comparison, a study of 191 inpatients with COVID-19 in Wuhan, China, yielded a mortality rate of 67% for those with known high-risk medical comorbidities, and 33% for those without any of these comorbidities [3].
T93 1119-1284 Sentence denotes In two large studies, overall mortality rates for patients with COVID-19 admitted to hospitals in China and the United Kingdom were 28% and 26%, respectively [3,17].
T94 1285-1564 Sentence denotes Thus, although dementia and parkinsonism in our cohort were associated with significant mortality, higher than that reported in general populations, the rates were not as high as has been reported in patients with other comorbidities known to correlate with unfavorable outcomes.
T95 1565-1803 Sentence denotes Within our cohort of patients with movement disorders, factors related to increased mortality were age over 60 years, PD or parkinsonism diagnosis, residing in an extended care facility, comorbid dementia, and comorbid medical conditions.