PMC:7551987 / 9286-11599 JSONTXT 3 Projects

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Id Subject Object Predicate Lexical cue
T57 0-4 Sentence denotes 2.2.
T58 5-22 Sentence denotes Model Description
T59 23-123 Sentence denotes The model is implemented via a set of ordinary differential equations, defined by Equations (1)–(6).
T60 124-322 Sentence denotes It implements viral free-living survival via the “Waterborne Abiotic or other Indirect Transmission (WAIT)” modelling framework, coupling individuals and the pathogen within the environment [23,24].
T61 323-566 Sentence denotes Within the model, the βw term allows for individuals to become infected via viral pathogen deposited in the environment and terms 𝜎A and 𝜎I allow asymptomatic and symptomatic individuals to deposit pathogens into the environment, respectively.
T62 567-929 Sentence denotes Adapted from the more traditional SEIR (susceptible-exposed-infected-recovered) model, the SEAIR-W (susceptible-exposed-asymptomatic-infected-recovered-WAIT) model interrogates the consequences of the two hypotheses outlined above while representing the dynamics of a very relevant disease system (SARS-CoV-2) that includes an asymptomatic infectious population.
T63 930-1087 Sentence denotes While the importance of asymptomatic transmission was debated early in the pandemic, many studies have affirmed its role in the spread of disease [25,26,27].
T64 1088-1344 Sentence denotes Though environmental transmission of SARS-CoV-2 remains a controversial topic, it is plausible that asymptomatic individuals may spread disease through frequent contact with the environment, thus increasing the proportion of virus that is free-living [28].
T65 1345-1510 Sentence denotes We acknowledge that mathematical models of epidemics can be limited by “identifiability,” which can obfuscate the relative importance of some routes of transmission.
T66 1511-1795 Sentence denotes In models that have both indirect and direct routes of transmission, it can be very difficult to conclude that one route is predominant [29,30,31]. (1) dSdt=μN−S−βAA+βIIN+βWWS (2) dEdt=βAA+βIIN+βWWS−ε+μE (3) dAdt=εE−ω+μA (4) dIdt=1−pωA−v+μII (5) dRdt=pωA+vI−μR (6) dWdt=σAA+σIIN1−W−kW
T67 1796-1853 Sentence denotes Figure 1 depicts the compartmental diagram for the model.
T68 1854-1961 Sentence denotes The direction of the arrows corresponds to the flow of the individuals and the pathogen through the system.
T69 1962-2150 Sentence denotes Note that individuals can move directly from the asymptomatically infected compartment to the recovered compartment (bypassing the symptomatic compartment) via what we call a “mild track”.
T70 2151-2212 Sentence denotes The dashed arrows represent WAIT coupling to the environment.
T71 2213-2313 Sentence denotes The model is inspired by one developed to interrogate environmental transmission of SARS-CoV-2 [22].