PMC:7551987 / 3595-4572 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T23 0-155 Sentence denotes Alternatively, the “tradeoff” hypothesis suggests that there is some intermediate level of parasite virulence [3,6,14] that is optimal for a given setting.
T24 156-276 Sentence denotes In this scenario, too high a virulence kills the host and parasite and too low a virulence leads to failure to transmit.
T25 277-499 Sentence denotes Applying this hypothesis specifically to free-living survival would suggest that selection for increased free-living survival should come at the expense of virulence (producing a pathogen that is less harmful to the host).
T26 500-642 Sentence denotes Mechanistically, as a consequence of increased adaptation to a nonhost environment, a virus may be less fit to replicate inside a host [9,15].
T27 643-789 Sentence denotes For example, a more robust viral capsid may help to survive harsh environmental conditions but may make it more difficult to package RNA/DNA [15].
T28 790-977 Sentence denotes More generally, the tradeoff hypothesis can be framed in the context of a life-history tradeoff: investment in certain parts of the life cycle often comes at the expense of others [2,16].