LitCovid-sentences  

PMC:7546716 / 25707-28450 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T91 0-109 Sentence denotes IL-33 might induce numerous cytokines and chemokines as well as its own receptor, ST2, in various cell types.
T92 110-351 Sentence denotes In asymptomatic or paucisymptomatic patients, IL-33 might expand anti-inflammatory Foxp3+ Treg cells or induce IL-4 production by GATA3+Foxp3+ Tregs and ILC2, thus stimulating mast cells, which might account for minor, allergy-like symptoms.
T93 352-546 Sentence denotes In individuals with mild-to-moderate disease, IL-33 (along with TGFβ) might induce ILC2 to release large amounts of IL-9, driving local expansion of effector memory Vγ9Vδ2+ T cells in the lungs.
T94 547-702 Sentence denotes In moderate–to-severe pneumonia, IL-33 combined with IL-2 and IL-7 from dendritic cells might further expand ILC2, γδT cells, and GM-CSF-producing T cells.
T95 703-826 Sentence denotes In severe–critical COVID-19, IL-33, GM-CSF, and IL-1 might stimulate each other's release by acting on multiple cell types.
T96 827-1053 Sentence denotes IL-33 induction of cytokines, chemokines, adhesion molecules, tissue factor, and neutrophil extracellular traps might contribute to endothelialitis, thrombosis, and extrapulmonary involvement in patients with MAS-like disease.
T97 1054-1333 Sentence denotes Neutrophil extracellular traps and mast cell degranulation could provoke protease-mediated cleavage of IL-33 into a 10–30 times more potent form, and IL-33-induced release of its soluble receptor ST2 might further polarise T cells and contribute to cardiovascular manifestations.
T98 1334-1598 Sentence denotes In patients who survive, IL-33 might drive the post-acute fibrotic phase thorugh induction of IL-13 and TGFβ in M2-differentiated macrophages and ILC2, thereby stimulating myofibroblasts and eliciting the epithelial–to–mesenchymal transition of type 2 pneumocytes.
T99 1599-1762 Sentence denotes Molecules inside brackets are part of self-amplifying proinflammatory loops fed by IL-33 and outside brackets indicate different factors possibly induced by IL-33.
T100 1763-1870 Sentence denotes Question mark indicates the uncertainty of whether mast cells produce IL-33. bFGF=fibroblast growth factor.
T101 1871-1902 Sentence denotes CCL=C-C motif chemokine ligand.
T102 1903-1940 Sentence denotes CTGF=connective tissue growth factor.
T103 1941-1975 Sentence denotes CXCL=C-X-C motif chemokine ligand.
T104 1976-2055 Sentence denotes DIC=(systemic vascular thromboses mimicking) diffuse intravascular coagulation.
T105 2056-2094 Sentence denotes EMT=epithelial-mesenchymal transition.
T106 2095-2121 Sentence denotes Foxp=forkhead box protein.
T107 2122-2147 Sentence denotes GATA=GATA-binding factor.
T108 2148-2192 Sentence denotes G-CSF=granulocyte colony-stimulating factor.
T109 2193-2249 Sentence denotes GM-CSF=granulocyte-macrophage colony-stimulating factor.
T110 2250-2274 Sentence denotes ICU=intensive care unit.
T111 2275-2290 Sentence denotes IFN=interferon.
T112 2291-2306 Sentence denotes IL=interleukin.
T113 2307-2340 Sentence denotes ILC2=type 2 innate lymphoid cell.
T114 2341-2376 Sentence denotes MAS=macrophage activation syndrome.
T115 2377-2404 Sentence denotes MOF=multiple organ failure.
T116 2405-2439 Sentence denotes NET=neutrophil extracellular trap.
T117 2440-2476 Sentence denotes PDGF=platelet-derived growth factor.
T118 2477-2574 Sentence denotes P/F ratio=arterial oxygen partial pressure to fractional inspired oxygen ratio. sST2=soluble ST2.
T119 2575-2592 Sentence denotes ST2=ST2 receptor.
T120 2593-2624 Sentence denotes TGF=transforming growth factor.
T121 2625-2646 Sentence denotes TF-1=tissue factor-1.
T122 2647-2674 Sentence denotes TNF=tumour necrosis factor.
T123 2675-2719 Sentence denotes TRAIL=TNF-related apoptosis-inducing ligand.
T124 2720-2743 Sentence denotes Treg=regulatory T cell.