PMC:7546139 / 11339-18596 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T127 0-34 Sentence denotes Methods to control carious lesions
T128 36-46 Sentence denotes Prevention
T129 47-259 Sentence denotes Primary preventive approaches (also known as non-invasive strategies for the management of caries) can reduce the risk of progressive dental tissue loss and avoid the need for treatments using rotary instruments.
T130 260-430 Sentence denotes The main preventive approaches have to be through the community and home, with behavioural components such as sugar restriction, plaque removal and oral health education.
T131 431-499 Sentence denotes Clinicians hold a pivotal role in supporting oral health behaviours.
T132 500-583 Sentence denotes For remineralisation, fluoride-based agents are accepted as the primary medicament.
T133 584-718 Sentence denotes Although there is less supporting evidence, other remineralisation agents such as self-assembling peptide P11-428 might be considered.
T134 719-952 Sentence denotes Preventive sealants cover plaque-retentive areas, occlusal fissures and pits, which are most vulnerable to caries.29,30 However, resin-based sealants involve a washing step to remove the acid etch thoroughly, generating some aerosol.
T135 953-1126 Sentence denotes Nevertheless, this risk can be avoided by using low-viscosity or high-viscosity glass-ionomer cement (LVGICS/HVGIC) and excess material can be removed with hand instruments.
T136 1127-1226 Sentence denotes A Cochrane review found no difference in the preventive effect of resin, LVGIC or HVGIC sealants.30
T137 1228-1243 Sentence denotes Early detection
T138 1244-1398 Sentence denotes The purpose of treating dental caries is primarily to stop its progression within the tooth as well as restoring the lost dental hard tissues when needed.
T139 1399-1524 Sentence denotes Early detection of carious lesions will reduce the need for aerosol-producing restorative care required for advanced lesions.
T140 1525-1665 Sentence denotes In addition, patients with active dental caries need to have their disease risks addressed as part of the long-term disease management.31,32
T141 1667-1718 Sentence denotes Non-restorative cavity control for dentinal lesions
T142 1720-1749 Sentence denotes What it is and when to use it
T143 1750-1849 Sentence denotes NRCC is a method of using 'cleaning' to prevent biofilm maturation and carious lesions progression.
T144 1850-2000 Sentence denotes It can be used for dentinal carious lesions in the primary and permanent dentition, root carious lesions and cavitated coronal smooth surface lesions.
T145 2002-2041 Sentence denotes How it works and clinical effectiveness
T146 2042-2168 Sentence denotes By making the carious surface accessible and having plaque frequently and thoroughly removed, the carious process will arrest.
T147 2169-2877 Sentence denotes In primary teeth, the effectiveness of NRCC in medium and large cavities together with ART restorations in small cavities has been tested in comparison to amalgam and ART restorations.33 Tooth survival after 3.5 years was 89% and not significantly different from either amalgam (91%) or ART restorations (90%), and in a randomised control trial of occluso-proximal cavitated lesions, survival (of pulp and tooth) was 92% at 2.5 years compared to 98% for teeth treated with the HT.34 NRCC has a less robust evidence base than the other treatment options discussed in this paper, with most of the reports of success being related to particular situations and carried out by dentists who support this technique.
T148 2878-3062 Sentence denotes The choice to use NRCC is less dependent on the shape or type of lesion than it is on the attitude of the patient towards prevention and the skill of the dentist in behaviour change.35
T149 3064-3075 Sentence denotes Non-AGP use
T150 3076-3223 Sentence denotes NRCC consists of three concurrent stages:Working with the patient to make plaque control more successful (improving oral hygiene procedure/habits).
T151 3224-3331 Sentence denotes The patient has to be ready to change behaviours that led to development of the disease in the first place.
T152 3332-3481 Sentence denotes Success depends on the clinician's ability to change the patient's (or in the case of a child, the parent's) behaviour towards taking responsibility.
T153 3482-3742 Sentence denotes So, 'prevention' becomes very much more than simply providing instruction of what to do (knowledge) and how to do it (skills), but has to involve an aspect of refocusing the patient to feeling empowered to make a difference to their own oral health (attitude).
T154 3743-3883 Sentence denotes Daily removal or disruption of the biofilm by brushing with a fluoridated toothpaste will slow down the carious process and can even halt it
T155 3884-3990 Sentence denotes Creating a cavity shape where the carious biofilm/dentine is accessible to a toothbrush (lesion exposure).
T156 3991-4043 Sentence denotes In some cases, overhanging enamel has to be removed.
T157 4044-4147 Sentence denotes To avoid use of rotary instruments, hand instruments can be used to gain access to the lesion (see ART)
T158 4148-4428 Sentence denotes Treatment with 38% SDF and/or a 5% NaF varnish therapy to reduce carious activity and promote remineralisation.33 These additional measures can support success of the NRCC approach if the carious lesion is active or there is increased risk that carious lesion activity will recur.
T159 4429-4544 Sentence denotes In the primary dentition, the goal is to avoid the lesion causing pain and/or infection until the tooth exfoliates.
T160 4545-4790 Sentence denotes For the permanent dentition, with grossly broken down teeth, root carious lesions or coronal smooth surface lesions, the main goal is to avoid the lesions leading to pain and/or infection while also avoiding or delaying the need for restoration.
T161 4792-4815 Sentence denotes SDF for dentine lesions
T162 4817-4846 Sentence denotes What it is and when to use it
T163 4847-5051 Sentence denotes SDF is a clear, colourless liquid that arrests active cavitated carious lesions and remineralises demineralised enamel and dentine.36 Some products have a blue tint, but these are not available in the UK.
T164 5052-5197 Sentence denotes Although licensed to treat dentine sensitivity in the UK and some other countries, it is more usually used 'off-label' to arrest carious lesions.
T165 5198-5390 Sentence denotes It turns active carious lesions black; therefore, consent to treatment must be obtained and it must be handled with care as it will temporarily stain skin, mucosa and most surfaces on contact.
T166 5391-5621 Sentence denotes SDF is an effective way of treating active lesions for primary and permanent teeth (coronal dentine and root).37,38 It can be used opportunistically while the patient is in the dental chair by applying to other high-risk surfaces.
T167 5622-5985 Sentence denotes SDF is effective in arresting early childhood caries39 and exposed root surfaces.40 It is more successful when used in cleansable lesions and accessible areas of the mouth.41 When caries is more severe or affects multiple teeth, repeated applications of SDF controls the disease (for example, applied after two weeks and six weeks, then six months as required).42
T168 5987-6026 Sentence denotes How it works and clinical effectiveness
T169 6027-6399 Sentence denotes SDF penetrates infected dentine,43 making the lesion twice as hard as healthy dentine.44 It produces a dense superficial layer and fills in micro-cavities with solid metallic silver.45 It also acts directly on the plaque biofilm,46,47 inhibiting bacterial growth.48,49 Removing carious tissue before SDF application is not necessary as it does not improve caries arrest.50
T170 6400-6746 Sentence denotes SDF has been shown to have some effect in preventing carious lesions in primary teeth, with one review showing that, by applying it at least once per year, 61% of new caries lesions might be prevented.51 SDF is clinically effective as well as cost-effective, and has the advantage of combined use with all other caries management techniques.51,52
T171 6748-6759 Sentence denotes Non-AGP use
T172 6760-6797 Sentence denotes Carious tissue is not removed at all.
T173 6798-6942 Sentence denotes To minimise droplet and aerosol production, the surface is dried with cotton instead of compressed air, then SDF is applied using a micro brush.
T174 6943-7093 Sentence denotes Arresting lesions using SDF can provide a solid foundation for restorations53,54 and can be combined with ART in primary or permanent teeth or the HT.
T175 7094-7257 Sentence denotes There are currently no clinical trials of efficacy, so combinations may be thought of as a 'belt and braces' approach to synergise the benefits of both treatments.