| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T79 |
0-78 |
Sentence |
denotes |
The meaning of SARS-CoV-2 RNA positivity in the CSF of our patient is unclear. |
| T80 |
79-177 |
Sentence |
denotes |
A direct effect of the virus, with normal proteins and no pleocytosis in the CSF, is questionable. |
| T81 |
178-522 |
Sentence |
denotes |
Viral neurotropism has been largely theorized, and virus particles have been observed to cross the capillary endothelium of the brain blood barrier (BBB) [10], but direct implication of SARS-CoV-2 in neurological manifestations is controversial, and viral RNA in the CSF of patients with neurological complications is only rarely detected [11]. |
| T82 |
523-710 |
Sentence |
denotes |
In a recent study including 31 patients with neurological manifestations, none had CSF viral positivity, but many had signs of disturbance of the blood brain barrier (BBB) integrity [12]. |
| T83 |
711-881 |
Sentence |
denotes |
Our patient showed signs of mild damage of the BBB as well, which might also be a possible consequence of systemic inflammation, in a patient with multiple organ failure. |
| T84 |
882-1039 |
Sentence |
denotes |
Therefore, an indirect mechanism of neurovascular unit breakdown, resulting in a passage of the virus in the CSF through the damaged BBB, cannot be excluded. |
| T85 |
1040-1099 |
Sentence |
denotes |
Contamination or artifact could also be a possibility [11]. |
