Id |
Subject |
Object |
Predicate |
Lexical cue |
T14 |
0-45 |
Sentence |
denotes |
Herd immunity is an end state, not a strategy |
T15 |
46-183 |
Sentence |
denotes |
Herd immunity has been widely bashed as the ‘failed strategy’ that the UK followed before changing tack and imposing a national lockdown. |
T16 |
184-422 |
Sentence |
denotes |
The ensuing controversy has all but poisoned this scientific term, which just refers to a state where the number of people immune in a population is so high that a pathogen cannot find enough susceptibles to infect and gradually dies out. |
T17 |
423-503 |
Sentence |
denotes |
In reality, herd immunity is the only possible endgame of the COVID-19 pandemic. |
T18 |
504-796 |
Sentence |
denotes |
Given the worldwide extent of viral spread and the large degree of asymptomatic or mildly symptomatic transmission [1], containing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in the same way that Ebola or SARS-CoV-1 were managed is beyond the realms of possibility. |
T19 |
797-962 |
Sentence |
denotes |
Therefore, the pandemic will only definitively end once herd immunity is reached, whether that be through vaccination, natural infection or a mixture of the two [2]. |
T20 |
963-1153 |
Sentence |
denotes |
Furthermore, even a modest degree of population immunity, at levels below those required for herd immunity, still results in a proportional reduction in the transmissibility of the pathogen. |
T21 |
1154-1302 |
Sentence |
denotes |
Therefore, it does help to bring the effective reproduction (R) number <1 and reverse the course of the pandemic, alongside proper control measures. |
T22 |
1303-1465 |
Sentence |
denotes |
This suggests that countries that had more infections in the first pandemic wave may face fewer challenges in controlling a potential second wave, and vice versa. |
T23 |
1466-1647 |
Sentence |
denotes |
An important caveat is that the duration of protective immunity after natural infection with SARS-CoV-2 is not currently known, and is one of the most urgent questions for research. |
T24 |
1648-1786 |
Sentence |
denotes |
Antibodies have been shown to last for at least a few months [3], and T-cell responses are likely to persist for several years more [4,5]. |
T25 |
1787-1988 |
Sentence |
denotes |
Nevertheless, if people can be reinfected with SARS-CoV-2 within a few years, the virus could become endemic like other seasonal respiratory viruses (e.g. influenza, respiratory syncytial virus, etc.). |
T26 |
1989-2133 |
Sentence |
denotes |
In such a case, herd immunity might only be achievable through vaccination, which might have to be repeated in order to sustain immunity levels. |