PMC:7545298 / 1505-3638 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T14 0-45 Sentence denotes Herd immunity is an end state, not a strategy
T15 46-183 Sentence denotes Herd immunity has been widely bashed as the ‘failed strategy’ that the UK followed before changing tack and imposing a national lockdown.
T16 184-422 Sentence denotes The ensuing controversy has all but poisoned this scientific term, which just refers to a state where the number of people immune in a population is so high that a pathogen cannot find enough susceptibles to infect and gradually dies out.
T17 423-503 Sentence denotes In reality, herd immunity is the only possible endgame of the COVID-19 pandemic.
T18 504-796 Sentence denotes Given the worldwide extent of viral spread and the large degree of asymptomatic or mildly symptomatic transmission [1], containing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in the same way that Ebola or SARS-CoV-1 were managed is beyond the realms of possibility.
T19 797-962 Sentence denotes Therefore, the pandemic will only definitively end once herd immunity is reached, whether that be through vaccination, natural infection or a mixture of the two [2].
T20 963-1153 Sentence denotes Furthermore, even a modest degree of population immunity, at levels below those required for herd immunity, still results in a proportional reduction in the transmissibility of the pathogen.
T21 1154-1302 Sentence denotes Therefore, it does help to bring the effective reproduction (R) number <1 and reverse the course of the pandemic, alongside proper control measures.
T22 1303-1465 Sentence denotes This suggests that countries that had more infections in the first pandemic wave may face fewer challenges in controlling a potential second wave, and vice versa.
T23 1466-1647 Sentence denotes An important caveat is that the duration of protective immunity after natural infection with SARS-CoV-2 is not currently known, and is one of the most urgent questions for research.
T24 1648-1786 Sentence denotes Antibodies have been shown to last for at least a few months [3], and T-cell responses are likely to persist for several years more [4,5].
T25 1787-1988 Sentence denotes Nevertheless, if people can be reinfected with SARS-CoV-2 within a few years, the virus could become endemic like other seasonal respiratory viruses (e.g. influenza, respiratory syncytial virus, etc.).
T26 1989-2133 Sentence denotes In such a case, herd immunity might only be achievable through vaccination, which might have to be repeated in order to sustain immunity levels.