PMC:7543471 / 4997-9678 JSONTXT 14 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T53 0-21 Sentence denotes MATERIALS AND METHODS
T54 22-89 Sentence denotes The data were collected from 16 March 2020 to 8 May 2020 (54 days).
T55 90-165 Sentence denotes Until 25 March, we received referrals by telephone on a standard pro forma.
T56 166-314 Sentence denotes Thereafter, we used a dedicated electronic referral portal to cope with the increased demand—referapatient® (Bloomsbury Health Limited, London, UK).
T57 315-417 Sentence denotes The electronic-based referral system was user-friendly, secure and improved efficacy in communication.
T58 418-479 Sentence denotes It did not require additional training or hardware resources.
T59 480-559 Sentence denotes A team of 3 experienced intensive care consultants reviewed the ECMO referrals.
T60 560-732 Sentence denotes They provided direct advice and activated the retrieval team when necessary following multidisciplinary discussions with 2 other senior intensivists working alternate days.
T61 733-886 Sentence denotes Before considering ECMO support, as a prerequisite, referring units were advised to place the patient in a prone position to improve the ventilation [9].
T62 887-1034 Sentence denotes There was no specific time frame for patient to stay proned before considering for ECMO, decision was based on clinical progression of the patient.
T63 1035-1211 Sentence denotes To ascertain the candidacy of the patient for ECMO, the retrieval team initially assessed the patient in the ICU, and reviewed the chest radiographs and results of blood tests.
T64 1212-1342 Sentence denotes We obtained verbal consent for ECMO from the patient’s next of kin over the telephone explaining the risks and potential benefits.
T65 1343-1482 Sentence denotes When the decision is made to proceed with ECMO, our preference is that cannulation be performed in the referring hospital’s operating room.
T66 1483-1719 Sentence denotes We require a dedicated anaesthetist, theatre practitioner and a radiographer with an image intensifier from the referring team to insert a new central venous line on the left side of the neck and facilitate ECMO insertion, respectively.
T67 1720-1809 Sentence denotes A World Health Organization surgical safety checklist was completed prior to cannulation.
T68 1810-2013 Sentence denotes We observed the recommendations from the Extracorporeal Life Support Organization (that veno-venous ECMO (VV-ECMO) be initiated by staff personal protective equipment with full contact precautions) [10].
T69 2014-2136 Sentence denotes Before the patient arrived in the operating room, the ECMO retrieval team had scrubbed and donned the appropriate apparel.
T70 2137-2244 Sentence denotes The equipment was ready so the team could proceed immediately (Fig. 1) in case the patient became unstable.
T71 2245-2359 Sentence denotes Changing the patient from the prone to the supine position for cannulation was performed onto the operating table.
T72 2360-2712 Sentence denotes Under aseptic conditions, the femoral vessel was punctured percutaneously under directed ultrasound guidance and the old central line in the neck was rewired for insertion of the return cannula into the internal jugular vein (our preference is to insert return cannulas on the right side of the neck because of the straighter path to the right atrium).
T73 2713-2907 Sentence denotes Once the positions of both guide wires were confirmed with the image intensifier, systemic heparin was administered, initially 2500 IU and another 2500 IU if required based on body surface area.
T74 2908-2965 Sentence denotes We followed our institutional anticoagulation guidelines.
T75 2966-3167 Sentence denotes A higher than usual degree of anticoagulation may be indicated, and a case-by-case assessment of bleeding versus thrombotic risks is recommended pending further evidence in patients with COVID-19 [10].
T76 3168-3259 Sentence denotes The puncture site was then dilated sequentially to the appropriate diameter of the cannula.
T77 3260-3737 Sentence denotes For drainage, we used the femoral venous Maquet (BIOLINE coating) HLS cannula® (Getinge AB, Gothenburg, Sweden), type PVL-2555 with an outer diameter of 7.6–8.3 mm (23–25 Fr) and a maximum insertion length of 380–550 mm; it connects to standard 9.5 mm (3/8 inch) diameter tubing.The return internal jugular venous cannula used is the Maquet (BIOLINE coating) HLS arterial cannula® type PAS-1915 with an outer diameter of 6.3 mm (19 Fr) and a maximum insertion length of 150 mm.
T78 3738-3843 Sentence denotes It has 2 side holes with a perforation length of 10 mm and connects to standard 9.5 mm (3/8 inch) tubing.
T79 3844-3974 Sentence denotes The cannulae were fixed securely in position with 3 sutures and Hollister® dressings (Hollister Limited, Winnersh, Wokingham, UK).
T80 3975-4266 Sentence denotes We used Thoratec Levitronix® (Levitronix GmbH, Zurich, Switzerland) consoles and ranges of oxygenators depending on availability (Paragon® Chalice Medical Limited, Worksop, Nottinghamshire, UK; Eurosets® Eurosets S.R.L, Medolla, Italy and Medos hilite®, Inspiration Healthcare, Crawley, UK).
T81 4267-4276 Sentence denotes Figure 1:
T82 4278-4337 Sentence denotes Extracorporeal membrane oxygenator insertion trolley setup.
T83 4338-4525 Sentence denotes All patients were transferred by a dedicated ECMO ambulance service (Amvale Medical Transport Limited, Scunthorpe, UK) [11]; 2 vehicles were used for transfer to ensure social distancing.
T84 4526-4584 Sentence denotes A standardized ECMO report was recorded for every patient.
T85 4585-4681 Sentence denotes Management of ECMO in patients with COVID-19 was similar to that in standard patients with ECMO.