PMC:7543426 / 24779-26093 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T280 0-143 Sentence denotes Several publications have shown an association of the severity of the clinical expression of COVID-19 with the number of comorbidities present.
T281 144-318 Sentence denotes Cardiac involvement in severe COVID-19 pathogenesis has been well documented [23], and cardiac risk factors have been identified as risk factors for increased mortality [24].
T282 319-463 Sentence denotes In our study of the macroscopic and microscopic features of hearts we found several differences between patients with and without comorbidities.
T283 464-670 Sentence denotes The 4 cases without comorbidities showed pronounced pericarditis and inflammatory cells infiltrating adventitia, indicating that the heart can be compromised irrespective of previous cardiovascular disease.
T284 671-743 Sentence denotes Kidney injury has been reported in nearly 30% of COVID-19 patients [25].
T285 744-879 Sentence denotes We found that histopathological changes in kidney in patients without comorbidities appeared more severe that those with comorbidities.
T286 880-946 Sentence denotes Patients without comorbidities also showed greater hepatic injury.
T287 947-1157 Sentence denotes Whether these findings represent liver or kidney damage caused directly by SARS-CoV-2 itself or are a reflection of the consequences of an abnormal and excessive inflammatory response, requires definition [26].
T288 1158-1314 Sentence denotes Studies of other viral infections of the respiratory tract have shown that liver injury may be immune mediated or a result of direct cytopathic damage [27].