PMC:7543426 / 11080-13688 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T126 0-21 Sentence denotes Microscopic Findings.
T127 22-84 Sentence denotes A range of common lung findings were seen on light microscopy.
T128 85-298 Sentence denotes Parenchymal multifocal damage with intraalveolar exudative and proliferative inflammation (Figure 1A2), with fibrin, hyaline membranes (Figure 1A3) consistent with a diagnosis of diffuse alveolar damage (Table 3).
T129 299-504 Sentence denotes Organizing pneumonia with fibrosis and type II pneumocyte hyperplasia, amphophilic cytoplasm, large nuclei, and prominent nucleoli, were indicative of cytopathic virus-induced changes (Figure 1A3 and 1A4).
T130 505-649 Sentence denotes Fibroblastic foci consisting of loose organizing connective tissue reflective of alveolar duct fibrosis were seen (fibrotic phase) (Figure 1B1).
T131 650-777 Sentence denotes Other findings included: pleural fibrosis (Figure 1B4), vascular injury with thrombi (Figure 1B2), and vasculitis (Figure 1B3).
T132 778-1086 Sentence denotes A main feature was the presence of numerous inflammatory cells consisting of granulocytes (CD15+) (Supplementary Figure 1A1 and 1A2), macrophages (CD68+) (Supplementary Figure 1A3 and 1A4), and T lymphocytes (CD3+) infiltrating into alveolar septa and clustering around capillary vessels (Supplementary 1B1).
T133 1087-1199 Sentence denotes Immunohistochemistry showed the presence of both CD4+ and CD8+ T lymphocytes (Supplementary Figure 1B2 and 1B3).
T134 1200-1284 Sentence denotes Of note, lymphocytes were CD20− indicating an absence of infiltrating B lymphocytes.
T135 1285-1435 Sentence denotes Thrombi were present and immunohistochemistry showed the presence of platelet aggregates and megakaryocytes within thrombi (Supplementary Figure 1B4).
T136 1436-1444 Sentence denotes Table 3.
T137 1446-1469 Sentence denotes Histopathology Findings
T138 1470-1531 Sentence denotes Findings Group 1, No. (%) (n = 18) Group 2, No. (%) (n = 4)
T139 1532-1536 Sentence denotes Lung
T140 1537-1575 Sentence denotes  Hyaline membranes 8 (44.4) 2 (50.0)
T141 1576-1630 Sentence denotes  Hyperplasia of type II pneumocyte 11 (61.2) 4 (100)
T142 1631-1664 Sentence denotes  Alveolar plug 8 (44.4) 4 (100)
T143 1665-1709 Sentence denotes  Alveolar fibrin deposit 9 (50.0) 3 (75.0)
T144 1710-1742 Sentence denotes  Hemorrhage 10 (55.6) 2 (50.0)
T145 1743-1782 Sentence denotes  Inflammatory cells 13 (72.3) 4 (100)
T146 1783-1844 Sentence denotes  Diffuse alveolar damage, fibrotic phase 12 (66.7) 1 (25.0)
T147 1845-1879 Sentence denotes  Microthrombi 14 (77.8) 2 (50.0)
T148 1880-1910 Sentence denotes  Vasculitis 8 (44.4) 4 (100)
T149 1911-1958 Sentence denotes  Multinucleated giant cells 4 (22.3) 2 (50.0)
T150 1959-1966 Sentence denotes Cardiac
T151 1967-1999 Sentence denotes  Myocarditis 9 (50.0) 3 (75.0)
T152 2000-2031 Sentence denotes  Vasculitis 5 (27.8) 3 (75.0)
T153 2032-2077 Sentence denotes  Inflammatory infiltrate 13 (72.3) 3 (75.0)
T154 2078-2113 Sentence denotes  Focal necrosis 6 (33.4) 2 (50.0)
T155 2114-2146 Sentence denotes  Pericarditis 9 (50.0) 4 (100)
T156 2147-2185 Sentence denotes  Vascular fibrosis 4 (22.3) 2 (50.0)
T157 2186-2193 Sentence denotes Hepatic
T158 2194-2238 Sentence denotes  Inflammatory infiltrate 8 (44.4) 3 (75.0)
T159 2239-2270 Sentence denotes  Congestion 8 (44.4) 2 (50.0)
T160 2271-2301 Sentence denotes  Steatosis 9 (50.0) 3 (75.0)
T161 2302-2307 Sentence denotes Renal
T162 2308-2352 Sentence denotes  Inflammatory infiltrate 9 (50.0) 3 (75.0)
T163 2353-2392 Sentence denotes  Glomerulosclerosis 9 (50.0) 3 (75.0)
T164 2393-2434 Sentence denotes  Interstitial fibrosis 9 (50.0) 4 (100)
T165 2435-2442 Sentence denotes Splenic
T166 2443-2482 Sentence denotes  Congested red pulp 15 (83.4) 4 (100)
T167 2483-2523 Sentence denotes  Lymphoid hypoplasia 11 (61.2) 4 (100)
T168 2524-2535 Sentence denotes Bone marrow
T169 2536-2576 Sentence denotes  Megakaryocytes hyperplasia 0 2 (50.0)
T170 2577-2608 Sentence denotes  Adipocytes 7 (38.9) 1 (25.0)