PMC:7534795 / 50943-51970 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T419 0-188 Sentence denotes Currently, there are multiple in vitro experiments and preclinical studies being performed around the world to test novel COVID-19 therapies, which are quickly moving into clinical trials.
T420 189-338 Sentence denotes Importantly, the early efficacy results have been limited to small-scale clinical studies in which the safety profiles have not been well-identified.
T421 339-463 Sentence denotes The safety profiles will be critical for COVID-19 patients with underlying comorbidities such as cardiovascular dysfunction.
T422 464-625 Sentence denotes Therefore, as there is a need for rapid clinical translation and a wide use of novel therapies for COVID-19, continued attention to safety profiles is important.
T423 626-777 Sentence denotes The rapid spread of COVID-19 globally continues to impact susceptible populations, like elderly patients and individuals with underlying comorbidities.
T424 778-1027 Sentence denotes While underlying cardiovascular issues are impacted by COVID-19 infection, many existing and novel therapeutic strategies have direct adverse cardiovascular effects, highlighting the importance for consideration in new drug research and development.