| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T191 |
0-161 |
Sentence |
denotes |
Inflammation is well known to participate in various CVDs, such as atherosclerosis, coagulopathy, coronary artery disease and HF (Libby, Ridker, & Maseri, 2002). |
| T192 |
162-329 |
Sentence |
denotes |
In the majority of severe cases of COVID-19, the cytokine storm has been coupled with elevated levels of erythematosus sedimentation rate and C-reactive protein (CRP). |
| T193 |
330-534 |
Sentence |
denotes |
Subsequently, hypercoagulation and disseminated intravascular coagulation would present as thrombosis, thrombocytopenia and gangrene of the limbs (Siddiqi & Mehra, 2020; Zhang, Zhao, Zhang, et al., 2020). |
| T194 |
535-802 |
Sentence |
denotes |
The identification of key cytokines such as TNFα in patients with HF demonstrated a strong positive correlation between cytokines and the severity of left ventricular dilation/hypertrophy and left ventricular dysfunction (Dibbs et al., 2003; Janczewski et al., 2003). |
| T195 |
803-941 |
Sentence |
denotes |
Other evidence indicates increased IL-1β and IL-6 levels detected in patients with acute myocarditis and acute MI (Xu, Shi, et al., 2020). |
| T196 |
942-1140 |
Sentence |
denotes |
Increased IL-6 levels have been associated with long QT-syndrome in patients with systemic inflammation, leading to higher risks for arrhythmias such as torsade de pointes (Aromolaran et al., 2018). |
| T197 |
1141-1314 |
Sentence |
denotes |
As well, the level of IL-6 can be used as a predictor of adverse cardiovascular events after acute coronary syndrome and chronic HF (Fanola et al., 2017; Held et al., 2017). |
| T198 |
1315-1451 |
Sentence |
denotes |
The serum levels of IL-8 are increased in patients with acute MI and is associated with higher mortality rates (Cavusoglu et al., 2015). |
| T199 |
1452-1733 |
Sentence |
denotes |
Collectively, we can conclude there is a strong correlation between elevated inflammatory markers and the adverse cardiovascular outcomes observed in patients with COVID-19 suggesting the potential role of an inflammatory storm in the development and progression of cardiac injury. |
