PMC:7534795 / 21065-21726 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T136 0-74 Sentence denotes • Tocilizumab to mitigate cytokine storm • Prospective observational study
T137 75-114 Sentence denotes • Severe or critical COVID-19 infection
T138 115-138 Sentence denotes • 25 to 88 years of age
T139 139-179 Sentence denotes • N = 21 tocilizumab + standard therapy
T140 180-239 Sentence denotes • 42.9% had CVD • 4–8 mg/kg or 400 mg tocilizumab i.v. once
T141 240-368 Sentence denotes • 85.7% received single dose of tocilizumab, 14.3% required second dose within 12 h of first dose • Fever normalized within 24 h
T142 369-402 Sentence denotes • Reduced O2 therapy requirements
T143 403-439 Sentence denotes • Minimal improvement in IL-6 levels
T144 440-468 Sentence denotes • CT lung lesion improvement
T145 469-537 Sentence denotes • All patients discharged • Limited sample size and no control group
T146 538-661 Sentence denotes • Tocilizumab treatment in severe COVID-19 cases may improve clinical symptoms in hyperinflammatory state (Xu et al., 2020)