Id |
Subject |
Object |
Predicate |
Lexical cue |
T730 |
0-105 |
Sentence |
denotes |
In summary, COVID-19 is rapidly spreading around the globe and our understanding of the virus is limited. |
T731 |
106-228 |
Sentence |
denotes |
To date, there is no effective, approved therapy or vaccination to treat the disease or protect against its complications. |
T732 |
229-373 |
Sentence |
denotes |
Although the lungs are considered the main target organ of SARS-CoV-2, the virus can affect many other organs, leading to multiple organ damage. |
T733 |
374-465 |
Sentence |
denotes |
Cardiovascular injury has been noted as a protruding clinical feature in COVID-19 patients. |
T734 |
466-607 |
Sentence |
denotes |
The dysregulation of RAAS can lead to a harmful inflammatory response and worsening of cardiovascular consequences in patients with COVID-19. |
T735 |
608-746 |
Sentence |
denotes |
Therefore, intervention with drugs that counteract Ang II may have a potential role in preventing the deleterious cardiovascular outcomes. |
T736 |
747-1053 |
Sentence |
denotes |
Although increased ACE2 levels may raise the concern of increased SARS-CoV-2 infectivity, we propose here that n-3 PUFAs may be beneficial rather than harmful for cardiovascular outcomes in COVID-19 patients by limiting Ang II-induced detrimental signaling and enhancing Ang (1-7) cardioprotective effects. |