PMC:7530350 / 655-1498 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T9 0-7 Sentence denotes Results
T10 8-163 Sentence denotes Eleven studies provided data of IL-6 levels in patients with severe to critical COVID-19 (severe) and patients with mild to moderate COVID-19 (non-severe).
T11 164-218 Sentence denotes The included studies were of moderate to high quality.
T12 219-380 Sentence denotes The mean patients’ age was 60.9 years, ranging from 45.2 to 76.7 years in the severe group and 46.8 years, ranging from 37.9 to 61 years, in the nonsevere group.
T13 381-473 Sentence denotes Fifty-two percent were male in the severe group, as compared to 46% in the non-severe group.
T14 474-658 Sentence denotes An overall random effects meta-analysis showed significantly higher serum levels of IL-6 in the severe group than in the non-severe group with a mean difference of +23.1 pg/mL (95% CI:
T15 659-721 Sentence denotes 12.42–33.79) and the overall effect of 4.24 (P-value < 0.001).
T16 722-843 Sentence denotes Meta-regressions showed that neither age nor sex significantly influenced the mean difference of IL-6 between the groups.