PMC:7519301 / 25853-26991 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T157 0-7 Sentence denotes Fig. 5.
T158 9-307 Sentence denotes Mutations across SARS-CoV-2 S sequences. (A) Structure of SARS-CoV (5 × 58) (shown instead of SARS-CoV-2 for completeness of the Receptor Binding Motif [RBM]). (B–D) The three protomers in the closed SARS-CoV-2 S glycoprotein (Protein Data Bank ID code 6VXX) are colored in yellow, cyan, and white.
T159 308-401 Sentence denotes Sites with mutations are shown as spheres. (B) Near-identity of potential vaccine candidates.
T160 402-547 Sentence denotes The MRCA and Wuhan-Hu-1 reference sequences were identical, while the consensus derived from all circulating sequences showed a mutation (D614G).
T161 548-683 Sentence denotes Site 614 is located at the interface between two subunits. (C) Sequence segments that differed between human and pangolin or bat hosts.
T162 684-893 Sentence denotes Amino acid segments 439 to 455 and 482 to 501 impact receptor binding, while the 574 to 690 segment corresponds to the S2 cleavage site. (D) Sites with shared mutations across SARS-CoV-2 circulating sequences.
T163 894-1061 Sentence denotes The colors of the spheres correspond to the proportion of SARS-CoV-2 sequences that differed from the Wuhan-Hu-1 sequence (GISAID: EPI_ISL_402125, GenBank: NC_045512).
T164 1062-1138 Sentence denotes Mutations that were found only in one or two sequences were not represented.