Id |
Subject |
Object |
Predicate |
Lexical cue |
T95 |
0-45 |
Sentence |
denotes |
The S mutation D614G quickly became dominant. |
T96 |
46-448 |
Sentence |
denotes |
The mutation D614G was found in 69% of sequences sampled globally as of May 18, 2020, the second most frequent mutation in S was only found in ∼2% of sequences. (A) Number of sequences with D (gray) or G (purple) by continent and sampling date shown cumulatively through the outbreak. (B) Phylogenetic tree reconstructed from all of the ORFs showing the linkage between D614G in S and P4715L in ORF1ab. |
T97 |
449-479 |
Sentence |
denotes |
Tips are colored by continent. |
T98 |
480-703 |
Sentence |
denotes |
The phylogeny suggests that these mutations were linked to a bottleneck event when SARS-CoV-2 viruses were introduced in Europe; this mutation was first seen in Europe in a sequence sampled in Germany at the end of January. |
T99 |
704-1099 |
Sentence |
denotes |
There is no evidence that the increasing predominance of this mutation was caused by convergent selection events that would have occurred in multiple individuals. (C) Overall number of sequences with D614 or D614G across continents; the predominance of D614G in Europe is suggestive of a founder event. (D) Distribution of Hamming distances between sequences with D614, G614 or discordant pairs. |
T100 |
1100-1140 |
Sentence |
denotes |
The median is marked with a dashed line. |