PMC:7473770 / 46429-48983 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T379 0-45 Sentence denotes Medical information and correlative histology
T380 46-209 Sentence denotes Before recording tomographic scans, tissue sections of 2.5⁢μ⁢m thickness were cut from the top, stained by HE (hematoxylin and eosin) and imaged with a microscope.
T381 210-274 Sentence denotes Appendix 1—figure 1 shows the histological slice of each sample.
T382 275-382 Sentence denotes The imaged section is just above the upper plane of the 3D PC-CT reconstruction volume, but not part of it.
T383 383-403 Sentence denotes Appendix 1—figure 1.
T384 405-482 Sentence denotes Microscopic images of HE-stained histological sections of all samples (I–VI).
T385 483-604 Sentence denotes Histological slices show comparable morphologies to the virtual slices in Figure 3, which represent different z-position.
T386 605-616 Sentence denotes Scale bars:
T387 617-625 Sentence denotes 400⁢μ⁢m.
T388 626-850 Sentence denotes An overview of different morphological features identified by conventional HE histology and virtual 3D histology is presented in Appendix 1—figure 2, while Appendix 1—figure 3 presents a direct comparison for the same slice.
T389 851-927 Sentence denotes For this purpose, the sample was sectioned and stained after the PC-CT scan.
T390 928-1116 Sentence denotes Artery lumen, artery wall, erythrocytes, thrombus, alveolar septum, marcophage, hyaline membrane and black granules (anthracosis) are shown in Appendix 1—figure 2 for both imaging methods.
T391 1117-1228 Sentence denotes Contrast of the hyaline membrane is homogenous in both modalities, facilitating idetification and segmentation.
T392 1229-1381 Sentence denotes Erythrocytes are easily recognized by eye in the conventional histology image, due to the HE staining, but less well distinguished by virtual histology.
T393 1382-1542 Sentence denotes This results in a difficult differentiation between thrombus and blood stasis as well as a difficult identification of blood capillaries in the alveolar septum.
T394 1543-1699 Sentence denotes Importantly, however, feature identification can be confirmed by correlative 2d and 3D histology on the same section, as exemplified by Appendix 1—figure 3.
T395 1700-1720 Sentence denotes Appendix 1—figure 2.
T396 1722-1815 Sentence denotes Comparison of morphological features between conventional HE histology and virtual histology.
T397 1816-2080 Sentence denotes Artery lumen, artery wall, erythrocytes, thrombus, alveolar septum, macrophage, hyaline membrane and anthracotic pigments (i.e. the black granules) are presented on exemplary slices of different samples (I–VI) for conventional (left) and virtual histology (right).
T398 2081-2121 Sentence denotes Scale bars: left 200⁢μ⁢m, right 100⁢μ⁢m.
T399 2122-2142 Sentence denotes Appendix 1—figure 3.
T400 2144-2221 Sentence denotes Direct comparison of virtual and HE histology for an identical slice/section.
T401 2222-2350 Sentence denotes (top left) Region of interest of the parallel beam tomogram (Sample II). (bottom left) Corresponding HE stained histology slice.
T402 2351-2421 Sentence denotes Thrombi and erythrocytes can be identified in both imaging modalities.
T403 2422-2534 Sentence denotes The red square marks the position of the zoom tomogram, for which the corresponding slice is shown on the right.
T404 2535-2546 Sentence denotes Scale bars:
T405 2547-2554 Sentence denotes 50⁢μ⁢m.