Id |
Subject |
Object |
Predicate |
Lexical cue |
T319 |
0-101 |
Sentence |
denotes |
For each patient the stitched overview scans were analyzed with regard to structural characteristics. |
T320 |
102-324 |
Sentence |
denotes |
The 3D-reconstructions were first binned (2 × 2 × 2), and the tissue was then segmented from the surrounding paraffin using the segmentation software Ilastik (Berg et al., 2019), which was then further refined with MATLAB. |
T321 |
325-463 |
Sentence |
denotes |
In order to exclude single macrophages or detached tissue, only voxels connected to the tissue block were considered for the distance map. |
T322 |
464-579 |
Sentence |
denotes |
Further, the areas of the paraffin which represent air compartments were linked to the outside of the tissue block. |
T323 |
580-675 |
Sentence |
denotes |
Individual self-contained areas of paraffin (not connected to air) were excluded from the mask. |
T324 |
676-793 |
Sentence |
denotes |
Based on this segmentation, the distance to the nearest voxel containing oxygen was calculated for each tissue voxel. |
T325 |
794-866 |
Sentence |
denotes |
The tissue volume V is given by the sum of all voxels containing tissue. |
T326 |
867-957 |
Sentence |
denotes |
The surface area SA is defined by all tissue voxels with a distance of 1 pixel to the air. |
T327 |
958-1063 |
Sentence |
denotes |
From this information we calculated the specific surface(2) SV=SA/Vwith SA/V surface area volume -ratio. |
T328 |
1064-1172 |
Sentence |
denotes |
Further a characteristic length(3) Lc=V/SA⋅vxwith vx edge length of a voxel was determined for each sample. |
T329 |
1173-1308 |
Sentence |
denotes |
Additionally, the mean distance (dO2¯) from all tissue voxels to the closest air compartment and its standard deviation was calculated. |