PMC:7473770 / 40979-42287 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T319 0-101 Sentence denotes For each patient the stitched overview scans were analyzed with regard to structural characteristics.
T320 102-324 Sentence denotes The 3D-reconstructions were first binned (2 × 2 × 2), and the tissue was then segmented from the surrounding paraffin using the segmentation software Ilastik (Berg et al., 2019), which was then further refined with MATLAB.
T321 325-463 Sentence denotes In order to exclude single macrophages or detached tissue, only voxels connected to the tissue block were considered for the distance map.
T322 464-579 Sentence denotes Further, the areas of the paraffin which represent air compartments were linked to the outside of the tissue block.
T323 580-675 Sentence denotes Individual self-contained areas of paraffin (not connected to air) were excluded from the mask.
T324 676-793 Sentence denotes Based on this segmentation, the distance to the nearest voxel containing oxygen was calculated for each tissue voxel.
T325 794-866 Sentence denotes The tissue volume V is given by the sum of all voxels containing tissue.
T326 867-957 Sentence denotes The surface area SA is defined by all tissue voxels with a distance of 1 pixel to the air.
T327 958-1063 Sentence denotes From this information we calculated the specific surface(2) SV=SA/Vwith S⁢A/V surface area volume -ratio.
T328 1064-1172 Sentence denotes Further a characteristic length(3) Lc=V/SA⋅vxwith v⁢x edge length of a voxel was determined for each sample.
T329 1173-1308 Sentence denotes Additionally, the mean distance (dO2¯) from all tissue voxels to the closest air compartment and its standard deviation was calculated.