| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T19 |
0-204 |
Sentence |
denotes |
In this work, we want to demonstrate the potential of propagation-based phase contrast x-ray tomography as a tool for virtual 3D histology in general, and in particular for the histopathology of Covid-19. |
| T20 |
205-424 |
Sentence |
denotes |
Our work is based on the assertion that integration of 3D morphological information with well-established histology techniques can provide a substantial asset for unraveling the pathophysiology of SARS-Cov-2 infections. |
| T21 |
425-626 |
Sentence |
denotes |
To this end, we have collected x-ray tomography data from the same autopsies, which were previously studied by immunohistochemical analysis and measurements of gene expression (Ackermann et al., 2020). |
| T22 |
627-736 |
Sentence |
denotes |
We ask in particular, whether DAD and the morphology of blood vessels can be visualized and quantified in 3D. |
| T23 |
737-892 |
Sentence |
denotes |
This is a timely scientific question in Covid-19 research, especially in view of increased intussusceptive angiogenesis reported in Ackermann et al., 2020. |
| T24 |
893-1009 |
Sentence |
denotes |
Here we present first results obtained from the postmortem lung samples of six patients who succumbed from Covid-19. |
| T25 |
1010-1339 |
Sentence |
denotes |
We exemplify the capability of this approach by 3D visualization of the DAD with hyaline membrane formation, by mapping the 3D distribution and density of angiocentric inflammation (perivascular T-cell infiltration), and by providing histograms of characteristic distances from the tissue interior to the closest air compartment. |
