LitCovid-sentences  

PMC:7473770 / 35353-39069 JSONTXT 7 Projects

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Id Subject Object Predicate Lexical cue
T275 0-13 Sentence denotes (2–cone beam)
T276 14-300 Sentence denotes Holographic recordings with the divergent and coherence filtered beam emanating from a compound focusing system composed of a Kirkpatrick-Baez (KB) mirrors system and an x-ray waveguide, resulting in a FOV of 0.4 mm sampled at a pixel size of about 167 nm (depending on exact geometry).
T277 301-448 Sentence denotes Both configurations were implemented side-by-side, using the same fully-motorized tomography stage and mounting, as detailed in Frohn et al., 2020.
T278 449-503 Sentence denotes A sketch of both configurations is shown in Figure 1 .
T279 504-603 Sentence denotes First, parallel-beam overview scans were acquired of the entire tissue volume embedded in paraffin.
T280 604-832 Sentence denotes To this end a 3.5 mm biopsy punch was taken from the multi-sample tissue block, and then scanned in a stitching-mode yielding a large overview reconstruction, composed of up to 20 individual tomograms (depending on tissue size).
T281 833-1093 Sentence denotes To increase image quality and avoid artifacts related to region-of-interest (ROI) or local tomography, a selected 1 mm punch was then taken from the already scanned larger tissue cylinder, and re-scanned, first in the parallel- and then the cone-beam geometry.
T282 1094-1180 Sentence denotes Experimental and acquisition parameters used for the data shown are listed in Table 3.
T283 1181-1189 Sentence denotes Table 3.
T284 1191-1268 Sentence denotes Data acquisition parameters for x-ray phase-contrast tomography measurements.
T285 1269-1301 Sentence denotes Cone geometry Parallel geometry
T286 1302-1340 Sentence denotes FOV 0.4 mm × 0.35 mm 1.6 mm × 1.4 mm
T287 1341-1367 Sentence denotes Pixel size 167 nm 650 nm
T288 1368-1383 Sentence denotes z 01 125 mm -
T289 1384-1413 Sentence denotes z 12 4975 mm 10 mm − 100 mm
T290 1414-1450 Sentence denotes Regime holographic direct contrast
T291 1451-1483 Sentence denotes Rotation start-stop continuous
T292 1484-1509 Sentence denotes Exposure 2 s 0.035 ⁢ s
T293 1510-1546 Sentence denotes Total exposure ≃ 63 m i n ≃ 75 s
T294 1547-1688 Sentence denotes Volumetric flowrate 1.16 × 10 4 μ m / 3 s 3.75 × 10 7 μ m / 3 s The configuration for (1–parallel beam) is depicted in Figure 1c.
T295 1689-1959 Sentence denotes The high-resolution microscope detection system (Optique Peter, France) was based on a 50⁢μ⁢m thick LuAG:Ce scintillator imaged with a 10× magnifying microscope objective onto a sCMOS sensor (pco.edge 5.5, PCO, Germany), resulting in an effective pixel size of 0.65⁢μ⁢m.
T296 1960-2120 Sentence denotes The high photon flux density allowed for image acquisition with continuous motor movement, short acquisition time of 35 ms per frame, and a framerate of 20 fps.
T297 2121-2250 Sentence denotes Single-distance tomogram recordings with about 1500 projections, and flat images before and after the scan, took less than 2 min.
T298 2251-2448 Sentence denotes For these scans, the focusing optics (KB-mirrors and waveguide) as well as the fastshutter (Cedrat technologies) were moved out of the beam, and beam size was adjusted by the upstream slit systems.
T299 2449-2539 Sentence denotes To avoid detector saturation, the beam was attenuated by 4× single crystal silicon wafers.
T300 2540-2601 Sentence denotes The configuration for (2–cone beam) is depicted in Figure 1d:
T301 2602-2657 Sentence denotes The beam was focused by the KB-mirrors to about 300 nm.
T302 2658-3113 Sentence denotes To further reduce the secondary source size, to increase coherence, and to achieve a smooth wavefront for holographic illumination, an x-ray waveguide formed by 1 mm long lithographic channels in silicon with a cross-section of about 100 nm was positioned in the focal plane of the KB-mirrors, resulting in an exit flux of 1–4⋅109 photon/s (depending on alignment and storage ring), as measured with the single photon counting detector (Pilatus, Dectris).
T303 3114-3250 Sentence denotes The sample was positioned at variable (defocus) distances behind the focus (waveguide exit), typically z01=125mm for the first distance.
T304 3251-3452 Sentence denotes The geometrically magnified holograms were recorded by a fibre-coupled sCMOS sensor (Zyla HF 5.5 detector, Andor Technologies) with a customized 15⁢μ⁢m thick Gadox scintillator, and 6.5⁢μ⁢m pixel size.
T305 3453-3632 Sentence denotes The detector position at about z02=5100mm behind the focus resulted in a magnification of about M=41 (for the first defocus distance), and hence an effective pixel size of 167 nm.
T306 3633-3716 Sentence denotes 1442 projections were recorded, with a typical exposure time of 2 s per projection.