Id |
Subject |
Object |
Predicate |
Lexical cue |
T264 |
0-114 |
Sentence |
denotes |
Chronic kidney disease (CKD) seems to be associated with enhanced risk of severe COVID-19 infection and mortality. |
T265 |
115-237 |
Sentence |
denotes |
Cheng et al. evaluated the association between markers of renal impairment and death in a cohort of 701 COVID-19 patients. |
T266 |
238-436 |
Sentence |
denotes |
They found that 43.9% of patients admitted had proteinuria and 26.7% had hematuria, serum creatinine and blood urea nitrogen (BUN) levels were increased in 14.4% and 13.1% of patients, respectively. |
T267 |
437-532 |
Sentence |
denotes |
Estimated glomerular filtration rate < 60 mL/min per 1.73 m2was found in 13.1% of patients [8]. |
T268 |
533-815 |
Sentence |
denotes |
In particular, the authors have shown that, at univariate analysis the presence of proteinuria was associated with a 4 up to 11-fold increased risk of in-hospital death compared with COVID-19 patients without kidney damage, whereas hematuria increased the risk of death by 12 times. |
T269 |
816-895 |
Sentence |
denotes |
These hazard ratios (HR)were higher than risk factors such as advanced age (HR: |
T270 |
896-922 |
Sentence |
denotes |
2.43), severe disease (HR: |
T271 |
923-1239 |
Sentence |
denotes |
6.10) and remained significantly associated with mortality even after adjustment (therefore to multivariate analysis) by age, gender, disease severity, lymphocyte count, comorbidity, thus demonstrating that measures of kidney damage play a very important role in assessing prognosis of COVID-19 patients [8,102,103]. |