PMC:7464116 / 44426-45665 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T264 0-114 Sentence denotes Chronic kidney disease (CKD) seems to be associated with enhanced risk of severe COVID-19 infection and mortality.
T265 115-237 Sentence denotes Cheng et al. evaluated the association between markers of renal impairment and death in a cohort of 701 COVID-19 patients.
T266 238-436 Sentence denotes They found that 43.9% of patients admitted had proteinuria and 26.7% had hematuria, serum creatinine and blood urea nitrogen (BUN) levels were increased in 14.4% and 13.1% of patients, respectively.
T267 437-532 Sentence denotes Estimated glomerular filtration rate < 60 mL/min per 1.73 m2was found in 13.1% of patients [8].
T268 533-815 Sentence denotes In particular, the authors have shown that, at univariate analysis the presence of proteinuria was associated with a 4 up to 11-fold increased risk of in-hospital death compared with COVID-19 patients without kidney damage, whereas hematuria increased the risk of death by 12 times.
T269 816-895 Sentence denotes These hazard ratios (HR)were higher than risk factors such as advanced age (HR:
T270 896-922 Sentence denotes 2.43), severe disease (HR:
T271 923-1239 Sentence denotes 6.10) and remained significantly associated with mortality even after adjustment (therefore to multivariate analysis) by age, gender, disease severity, lymphocyte count, comorbidity, thus demonstrating that measures of kidney damage play a very important role in assessing prognosis of COVID-19 patients [8,102,103].