| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1187 |
0-228 |
Sentence |
denotes |
Exogenous mBDNF treatment has been found to mimic the pro-survival effect of glial CCR5 deficiency against Tat ± morphine, and its neuroprotective effects have been supported in other neurodegenerative disease models (Cai et al. |
| T1188 |
229-244 |
Sentence |
denotes |
2014; Xu et al. |
| T1189 |
245-251 |
Sentence |
denotes |
2018). |
| T1190 |
252-395 |
Sentence |
denotes |
Collectively, the findings suggest that the loss of CCR5 may fundamentally change MOR signaling in HIV-exposed glia in a BDNF-dependent manner. |
| T1191 |
396-596 |
Sentence |
denotes |
Thus, overall the interaction of opioid and chemokine receptors, specifically MOR and CCR5, may alter the neuropathogenesis of HIV in a qualitatively unique manner not seen with either disorder alone. |
