PMC:7463108 / 111202-111927 JSONTXT 8 Projects

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Id Subject Object Predicate Lexical cue
T1386 0-278 Sentence denotes Using experimental data from SIV-infected, morphine-addicted macaques, mathematical modeling suggests that morphine exposure increases the proportion of cells with high susceptibility to SIV infection, at least in part, because of increased co-receptor expression (Vaidya et al.
T1387 279-285 Sentence denotes 2016).
T1388 286-552 Sentence denotes In addition to promoting a higher steady state viral loads and larger CD4 count declines, the model also predicts that morphine exposure results in the need for more efficacious ARV treatment than would be necessary for animals not exposed to morphine (Vaidya et al.
T1389 553-559 Sentence denotes 2016).
T1390 560-725 Sentence denotes Although the direct impact of morphine on ARV concentrations was not investigated, the study provides evidence supporting morphine’s negative impact on ARV efficacy.