PMC:7461420 / 9786-10677 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T111 0-133 Sentence denotes The interruption of any stage of the viral life cycle can become an important therapeutic approach for treating CoV‐related diseases.
T112 134-313 Sentence denotes A recent SARS‐CoV‐2‐human protein‐protein interaction analysis showed that SARS‐CoV‐2 contains approximately 66 druggable proteins, each of which has several ligand binding sites.
T113 314-429 Sentence denotes 25 The most interesting coronavirus proteins are the S glycoprotein, proteases Mpro and PLpro, RdRP, and helicase.
T114 430-582 Sentence denotes In this review, we highlight these targets with potential therapeutic development against the highly dangerous pathogens SARS‐CoV‐1 and 2, and MERS‐CoV.
T115 583-697 Sentence denotes Medicinal chemistry efforts toward the evolution of molecules with drug‐like properties is additionally discussed.
T116 698-891 Sentence denotes In addition, broad‐spectrum antivirals targeting the major viruses are reviewed in detail, since they represent a highly promising strategy for treating these often fatal respiratory illnesses.