Id |
Subject |
Object |
Predicate |
Lexical cue |
T111 |
0-133 |
Sentence |
denotes |
The interruption of any stage of the viral life cycle can become an important therapeutic approach for treating CoV‐related diseases. |
T112 |
134-313 |
Sentence |
denotes |
A recent SARS‐CoV‐2‐human protein‐protein interaction analysis showed that SARS‐CoV‐2 contains approximately 66 druggable proteins, each of which has several ligand binding sites. |
T113 |
314-429 |
Sentence |
denotes |
25 The most interesting coronavirus proteins are the S glycoprotein, proteases Mpro and PLpro, RdRP, and helicase. |
T114 |
430-582 |
Sentence |
denotes |
In this review, we highlight these targets with potential therapeutic development against the highly dangerous pathogens SARS‐CoV‐1 and 2, and MERS‐CoV. |
T115 |
583-697 |
Sentence |
denotes |
Medicinal chemistry efforts toward the evolution of molecules with drug‐like properties is additionally discussed. |
T116 |
698-891 |
Sentence |
denotes |
In addition, broad‐spectrum antivirals targeting the major viruses are reviewed in detail, since they represent a highly promising strategy for treating these often fatal respiratory illnesses. |