| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T647 |
0-154 |
Sentence |
denotes |
Using MS/MS analysis, they deduced that ebselen (153) and 156 are irreversible inhibitors of Mpro by covalently attaching to Cys145 of the catalytic dyad. |
| T648 |
155-231 |
Sentence |
denotes |
Molecular docking was used to illustrate how 151, 154, and 155 bind to Mpro. |
| T649 |
232-396 |
Sentence |
denotes |
Antiviral activity assays, using real‐time reverse transcription‐PCR, indicated that ebselen and inhibitor “N3” (40; Figure 12) had the strongest antiviral effects. |
| T650 |
397-511 |
Sentence |
denotes |
Ebselen displayed an EC50 value of 4.67 µM, and “N3” showed an EC50 value of 16.77 µM in a plaque‐reduction assay. |
| T651 |
512-577 |
Sentence |
denotes |
Ebselen's IC50 value for SARS‐CoV‐2 Mpro was reported at 0.67 µM. |
| T652 |
578-646 |
Sentence |
denotes |
The activity data of remaining compounds is summarized in Figure 35. |
