Id |
Subject |
Object |
Predicate |
Lexical cue |
T638 |
74-171 |
Sentence |
denotes |
Among them, the two best compounds 147 and 148 display IC50 values of 0.3 and 3 µM, respectively. |
T639 |
172-289 |
Sentence |
denotes |
A variety of SARS‐CoV‐1 Mpro inhibitors have been identified through virtual screening (VS) as an alternative to HTS. |
T640 |
290-404 |
Sentence |
denotes |
VS of 50 240 structurally diverse small molecules allowed to identify 104 molecules with anti‐SARS‐CoV‐1 activity. |
T641 |
405-556 |
Sentence |
denotes |
Compound 149 (Figure 34) demonstrated potent enzyme inhibition (IC50, 2.5 μM) and an EC50 of 7 μM in Vero cell‐based SARS‐CoV‐1 plaque reduction assays |