| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T557 |
0-12 |
Sentence |
denotes |
Ghosh et al. |
| T558 |
13-188 |
Sentence |
denotes |
172 studied the SARs of halopyridinyl indole carboxylates and identified a series of analogs (96–101; Figure 27) as SARS‐CoV‐1 Mpro inhibitors in the nanomolar potency range. |
| T559 |
189-308 |
Sentence |
denotes |
The best derivative (100) had high enzymatic inhibitory potency (IC50, 0.030 µM) and antiviral activity (EC50, 6.9 µM). |
| T560 |
309-427 |
Sentence |
denotes |
Compound 97 was also observed to inhibit the MERS‐CoV Mpro both in enzymatic and cell‐based (EC50, 12.5 µM) bioassays. |
| T561 |
428-514 |
Sentence |
denotes |
173 This molecule covalently modified Mpro, which was confirmed by MALDI‐TOF studies. |
