PMC:7461420 / 44920-45323 JSONTXT 6 Projects

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Id Subject Object Predicate Lexical cue
T408 0-309 Sentence denotes Although the above‐described inhibitors with 1,4‐Michael acceptors (e.g., α,β‐vinyl ethyl ester, –CH═CH–C(O)–OEt) showed enzymatic or cell‐based in‐vitro activities, they can be cleaved to their carboxylic acids by plasma esterases; for instance, AG7088 (29) was inactive in the plasma of rodents and rabbits.
T409 310-403 Sentence denotes 144 , 145 Therefore, scientists explored different reactive groups that are stable in vivo.