| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T198 |
0-168 |
Sentence |
denotes |
ACE, a highly glycosylated type I integral membrane protein, is an essential component of the renin‐angiotensin (Ang) system, which controls blood pressure homeostasis. |
| T199 |
169-208 |
Sentence |
denotes |
Both ACE1 and ACE2 cleave Ang peptides. |
| T200 |
209-356 |
Sentence |
denotes |
However, they differ markedly: ACE1 cuts and converts the inactive decapeptide Ang I into the octapeptide Ang II by removing the dipeptide His‐Leu. |
| T201 |
357-610 |
Sentence |
denotes |
This Ang II induces vaso‐ and bronchoconstriction, increased vascular permeability, inflammation, and fibrosis, thus promoting acute respiratory distress syndrome (ARDS) and lung failure in patients infected with SARS‐CoV‐1 or SARS‐CoV‐2 57 (Figure 5). |
| T202 |
611-742 |
Sentence |
denotes |
Therefore, ACE‐inhibitors (ACEis) and angiotensin II receptor blockers (ARBs) could block the disease‐propagating effect of Ang II. |
| T203 |
743-757 |
Sentence |
denotes |
58 , 59 , 60 |
