PMC:7461420 / 105609-106192 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T964 0-159 Sentence denotes Viral proteases are another very important target for the development of antiviral therapies, as they are directly involved in the viral replication processes.
T965 160-338 Sentence denotes Especially the Mpro is one of the best‐characterized viral targets, and numerous medicinal chemistry efforts have been already reported for the past outbreaks of SARS‐1 and MERS.
T966 339-457 Sentence denotes Main proteases are highly conserved among other CoVs, which allows the development of broad spectral antiviral agents.
T967 458-514 Sentence denotes Moreover, no human protease analog to the Mpro is known.
T968 515-583 Sentence denotes Thus, drugs targeting Mpro could be highly virus‐selective and safe.