PMC:7441777 / 44662-45692 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T442 0-106 Sentence denotes We have also analyzed the toxicity profiles for EGCG, TF2a, TF2b, TF3 as well as remdesivir (see Table 7).
T443 107-275 Sentence denotes The toxicity prediction from the AMES test (Salmonella typhimurium reverse mutation assay) exhibited that all the compounds could be considered as non-mutagenic agents.
T444 276-351 Sentence denotes High toxicity was observed for all the compounds in Tetrahymena pyriformis.
T445 352-462 Sentence denotes EGCG, TF2a, TF2b, TF3, and remdesivir were shown to inhibit the human ether-a-go-go-related gene II (hERG II).
T446 463-605 Sentence denotes However, Remdesivir has been shown to induce hepatotoxicity, whilst EGCG, TF2a, TF2b, TF3 are not likely to be associated with hepatotoxicity.
T447 606-787 Sentence denotes The maximum recommended tolerated dose (MRTD) in human prediction shows that remdesivir violate MRTD whereas natural polyphenol EGCG, TF2a, TF2b, TF3 do not fall into this category.
T448 788-942 Sentence denotes Remdesivir does not possess high acute toxicity whereas EGCG, TF2a, TF2b, and TF3 regarded as high acute toxic compound as it falls under minnow toxicity.
T449 943-1030 Sentence denotes Additionally, none of the compounds predicted to be associated with skin sensitization.