PMC:7435837 / 34787-37725 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T263 0-4 Sentence denotes 6.4.
T264 5-20 Sentence denotes Medical Devices
T265 21-200 Sentence denotes Seriously ill patients with respiratory distress, and also other patients with other conditions such as cardiovascular disease often require intimate contact with medical devices.
T266 201-350 Sentence denotes Examples of devices include prosthetic heart valves, orthopedic implants, intravascular catheters, artificial hearts, cardiac pacemakers, etc. [185].
T267 351-476 Sentence denotes Wettability of the surfaces has been shown to play a crucial role in the adhesion of viruses to whichever surface is present.
T268 477-649 Sentence denotes Glass slides were successfully coated with silanes of various hydrophobicity and showed that more hydrophobic surfaces were most efficient in capturing influenza A viruses.
T269 650-754 Sentence denotes This points again to a form of nanotrapping and inactivation of the virus by surface interactions [186].
T270 755-855 Sentence denotes Glass slides were also LbL coated with polyanionic and polycationic chitosan to eliminate S. aureus.
T271 856-958 Sentence denotes It was implied that this LbL process will benefit medical devices with antibacterial properties [187].
T272 959-1121 Sentence denotes Vascular prostheses were coated successfully with alternating layers of human serum albumin and the GAG, heparin, and other carbohydrates such as dextran sulfate.
T273 1122-1289 Sentence denotes These multilayered contacts prevented the clotting factor, fibrinogen from causing thrombosis which is a serious complication of contact with the medical device [188].
T274 1290-1725 Sentence denotes Although not always disclosing full information, self-eliminating coatings on medical devices that comprise mainly of polypeptides were successfully applied to medical devices that could deliver biological substances after implantation into the human body [189], applied to urethral catheters and stents to prevent mucosal tissue of the urethra to block openings of the catheter or stent that will lead to prevention of fluid drainage.
T275 1726-1832 Sentence denotes These coatings also released antimicrobials although antivirals were not mentioned specifically [190,191].
T276 1833-1994 Sentence denotes In a comprehensive review, the future of LbL nanocoating in the medical profession was pointed out, however, antiviral LbL applications were not mentioned [192].
T277 1995-2179 Sentence denotes It was interesting to find that LbL-nanocoating of medical devices also revealed very few literature entries and even fewer regarding coating with polysaccharides or antiviral coating.
T278 2180-2327 Sentence denotes It was reported that catheter silicon tubes that contained chlorohexidine-containing PEG-micelles were coated with poly(acrylic acid) as polyanion.
T279 2328-2422 Sentence denotes Again the purpose of this study was to afford antibacterial action to the silicon tubes [193].
T280 2423-2529 Sentence denotes Dental implants are another medical device that benefited from antibacterial LbL coating with PSS and PAH.
T281 2530-2659 Sentence denotes Metronidazole was coated in the final bilayer and this provided the antibacterial effect to prevent periodontal infections [194].
T282 2660-2812 Sentence denotes It is again apparent, at the time of writing, that antiviral coatings of medical devices have not been the main focus of research or innovation efforts.
T283 2813-2938 Sentence denotes Figure 5 depicts a summary of our suggested methods of contributing in an almost crude, passive way to curb viral infections.