| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T145 |
0-4 |
Sentence |
denotes |
5.2. |
| T146 |
5-51 |
Sentence |
denotes |
Employment of Polysaccharides as LbL Materials |
| T147 |
52-157 |
Sentence |
denotes |
In this paper, the focus will fall only on common GAGs and other common polysaccharides such as chitosan. |
| T148 |
158-410 |
Sentence |
denotes |
It was also noticed during our literature survey that the GAG, keratan sulfate has not been studied in LbL applications and can most probably be attributed to its production in the cornea, cartilage, and bone tissues which makes it fairly inaccessible. |
| T149 |
411-603 |
Sentence |
denotes |
To date, the GAGs and other polysaccharides have not been employed widely in LbL nanocoating to specifically produce antiviral surfaces as is the case for antibacterial or antifungal coatings. |
| T150 |
604-740 |
Sentence |
denotes |
Numerous publications have reported on the antibacterial surface application of polysaccharides via an LbL approach [85,86,87,88,89,90]. |
| T151 |
741-887 |
Sentence |
denotes |
Table 1 lists some commonly utilized polysaccharides that have been employed in LbL nanocoatings and a non-exhaustive list of recent applications. |
| T152 |
888-1041 |
Sentence |
denotes |
The reader should be able to realize that the LbL technique presents numerous possibilities for the application of polysaccharides as antiviral surfaces. |
| T153 |
1042-1113 |
Sentence |
denotes |
Firstly, the polysaccharides, especially GAGs are abundantly available. |
| T154 |
1114-1280 |
Sentence |
denotes |
Secondly, they can recognize and interact with proteins via a range of intermolecular forces including electrostatic, hydrogen bonding, and hydrophobic bonding [112]. |
| T155 |
1281-1439 |
Sentence |
denotes |
Thirdly, the polysaccharides are biological molecules and in the case of LbL applications, need minimal or no modification to perform their intended function. |
| T156 |
1440-1528 |
Sentence |
denotes |
Fourthly, fairly low quantities of material need to be deposited to coat the substrates. |
| T157 |
1529-1615 |
Sentence |
denotes |
Lastly, they are biocompatible, biodegradable, and most renewable sources of material. |
| T158 |
1616-1735 |
Sentence |
denotes |
It is very apt to illustrate the chemical structures of the GAGs and some other selected polysaccharides at this point. |
| T159 |
1736-1816 |
Sentence |
denotes |
Figure 4 shows the structures based on the official IUPAC recommendations [113]. |
| T160 |
1817-2018 |
Sentence |
denotes |
From Figure 4, it is observed that several anionic functional groups are available for electrostatic interaction, however, numerous hydroxyl and carbonyl groups are also available for hydrogen bonding. |
| T161 |
2019-2150 |
Sentence |
denotes |
The successful application of polysaccharides as antimicrobials now leads us to the possible preventative measures against viruses. |
