Id |
Subject |
Object |
Predicate |
Lexical cue |
T388 |
0-20 |
Sentence |
denotes |
Aging score analysis |
T389 |
21-164 |
Sentence |
denotes |
To assess the impact of aging in circulating immune cells, we selected the top 20 genes out of 60 common upregulated genes in all immune cells. |
T390 |
165-287 |
Sentence |
denotes |
Aging scores were estimated for all cells as the average of the scaled (Z-normalized) expression of the genes in the list. |
T391 |
288-416 |
Sentence |
denotes |
The score of aging for all immune cell types can be used to predict the effect of aging on single cells and cell subtype levels. |
T392 |
417-684 |
Sentence |
denotes |
Calculation of the scores was done as follows: the score of the aging gene set in the given cell-subset (named as X) was computed as the sum of all UMI for all the aging genes expressed in X cell, divided by the sum of all UMI expressed by X cell (Pont et al., 2019). |