Id |
Subject |
Object |
Predicate |
Lexical cue |
T378 |
0-249 |
Sentence |
denotes |
Differential expression analysis for each cell type between different groups (YA and AA in cohort-1 and YH, AH, YCR and ACR in cohort-3) was performed using the t-test as implemented in the ‘‘sc.tl.rank_genes_groups’’ function of the Scanpy package. |
T379 |
250-387 |
Sentence |
denotes |
For each cluster, differentially-expressed genes (DEGs) were performed using the t-test and generated relative to all of the other cells. |
T380 |
388-547 |
Sentence |
denotes |
Before executing the differential expression analysis, we filtered out the cell types that were missing or had fewer than three cells in the comparison groups. |
T381 |
548-817 |
Sentence |
denotes |
An aging-associated and disease-related DEG dataset was established (adjusted P value < 0.05, |Log2FC| > 0.25) after identification of DEGs between AA and YA groups in cohort-1, AH and YH groups in cohort-3, ACR and AH groups in cohort-3, YCR and YH groups in cohort-3. |
T382 |
818-934 |
Sentence |
denotes |
The ‘‘upregulated DEGs during aging’’ were defined as the DEGs that increased in AA group and decreased in YA group. |
T383 |
935-1049 |
Sentence |
denotes |
The ‘‘downregulated DEGs in aging’’ were defined as the DEGs that decreased in AA group and increased in YA group. |