Id |
Subject |
Object |
Predicate |
Lexical cue |
T123 |
0-144 |
Sentence |
denotes |
We next studied aging-associated DEGs in MCs and found enrichment in inflammatory genes, such as IL1B, TNF and CXCL8, in the AA group (Fig. 3A). |
T124 |
145-304 |
Sentence |
denotes |
All MC subsets had increased expression of the chemokines, TNF, IL1B and CDKN1A and decreased expression of SIGLEC14 and CLEC12A (Figs. 3G, S6A; Table S10A–C). |
T125 |
305-675 |
Sentence |
denotes |
Analysis of aging-related DEGs demonstrated that the CD14 MC subset was most affected by aging, as reflected by the increased NOD-like receptor signaling pathway, NF-κB signaling pathway, Toll-like receptor signaling pathway, inflammasome pathway, and MAPK pathway (Fig. 3H) and the obvious decrease in RNA splicing, autophagy, and vesicle-mediated transport (Fig. S7D). |