PMC:7417285 / 108-3647 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T2 0-240 Sentence denotes We read the recent European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastroenterology Nurses and Associates (ESGENA) Position Statement on gastrointestinal endoscopy and the COVID-19 pandemic with great interest.
T3 241-343 Sentence denotes The Statement provides guidance to protect against COVID-19 for both patients and endoscopy personnel.
T4 344-613 Sentence denotes We are concerned, however, that the general comment number 3 1 , which states, “Reprocessing of flexible endoscopes and endoscopic accessories should be performed according to published guidelines,” is not appropriate in the setting of COVID-19 contaminated endoscopes.
T5 614-793 Sentence denotes The ESGE and ESGENA guidelines in 2018 2 recommend a precleaning step, which, in the context of COVID-19 contamination, may cause endoscopy personnel to be unnecessarily splashed.
T6 794-974 Sentence denotes Therefore, during precleaning at the bedside 2 , we recommend first applying virucide to the endoscope control section and insertion tube by using a gauze dampened in 70 % alcohol.
T7 975-1110 Sentence denotes Second, to remove debris and to prevent biofilm formation in the endoscope channel, we recommend using enzymatic detergent solution 3 .
T8 1111-1255 Sentence denotes The use of enzymatic detergent is preferred because it reduces the amount of organic residue compared with the use of nonenzymatic detergent 4 .
T9 1256-1433 Sentence denotes Notably, we strongly recommend against suction or blowing air, or flushing water into any of the channels as these actions may cause splashing or even aerosolization ( Fig. 1 ).
T10 1434-1514 Sentence denotes Thus, we recommend only suctioning the detergent through the working channel 4 .
T11 1515-1645 Sentence denotes The valves should not be replaced before finishing this process because significant splashing may occur during the valve exchange.
T12 1646-1850 Sentence denotes Third, we recommend immersing the endoscope in a bin containing 0.2 % – 0.35 % paracetic acid, glutaraldehyde, or ortho-phthalaldehyde solution for the duration recommended by the manufacturer ( Fig. 1 ).
T13 1851-1881 Sentence denotes These solutions are virucidal.
T14 1882-2129 Sentence denotes Ultimately, the endoscope can be transferred to the reprocessing room and undergo the standard reprocessing order, starting from leak testing, repeat manual cleaning (this time with flushing, rinsing etc.), and standard high-level disinfection 2 .
T15 2130-2248 Sentence denotes Fig. 1  Endoscope reprocessing with additional measures for bedside endoscope cleaning during the COVID-19 outbreak.
T16 2249-2308 Sentence denotes PUI, person under investigation; OPA, ortho-phthalaldehyde.
T17 2310-2554 Sentence denotes The person who performs the bedside precleaning process should wear an enhanced set of personal protective equipment (PPE) and, in order to make best use of available PPE, that person can be the assistant who is already wearing appropriate PPE.
T18 2555-2648 Sentence denotes In such a situation, the person in the reprocessing room may wear standard PPE ( Fig. 2 ) 1 .
T19 2649-2789 Sentence denotes When the additional safety measures can only be performed in the reprocessing room, the person responsible must wear an enhanced set of PPE.
T20 2790-3134 Sentence denotes Fig. 2  Personal protective equipment (PPE) for the person who performs the bedside precleaning process and the person in the reprocessing room, according to 2020 position statements on COVID-19 from Asian Pacific Society of Digestive Endoscopy, American Society for Gastrointestinal Endoscopy, and Centers for Disease Control and Prevention.
T21 3135-3285 Sentence denotes To win the war against COVID-19, we must prevent all healthcare personnel from becoming infected and further spreading the virus to their communities.
T22 3286-3409 Sentence denotes As the standard protocol may cause splashing or even aerosolization, steps must be taken to mitigate the transmission risk.
T23 3410-3539 Sentence denotes While waiting for the study to prove the benefit of these additional steps, we believe that “to do more” is essential at present.