LitCovid-sentences  

PMC:7417198 / 4729-9639 JSONTXT 11 Projects

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Id Subject Object Predicate Lexical cue
T28 0-21 Sentence denotes Materials and methods
T29 23-40 Sentence denotes Patient selection
T30 41-203 Sentence denotes Our department, according to the actual COVID-19 protocol national guidelines, has suspended elective procedures and reviewed our criteria of prioritization [21].
T31 204-374 Sentence denotes Accordingly, we retain that a pituitary/skull base procedure can be considered non-deferrable upon the presence ofpituitary apoplexy associated with neurological defects;
T32 375-533 Sentence denotes tumors with massive suprasellar and/or supradiaphragmatic component with CSF circulation obstacle and/or hydrocephalus and/or intracranial hypertension signs;
T33 534-614 Sentence denotes At admission, patients are screened via interview and temperature is registered.
T34 615-825 Sentence denotes Upon any suspicion of COVID-19, the infectivologist will be consulted in order to rule out the workflow; in any case, whether delaying surgery increases risks, precautions as for positive patients are required.
T35 826-1049 Sentence denotes However, it should be minded that the certainty of COVID-19 negativity status is somehow difficult to assess: many COVID-19 cases are asymptomatic, and the reliability of screening tests is often limited and eventually low.
T36 1050-1571 Sentence denotes As general rule though, basic precautions, i.e., accurate and frequent hand washing, wearing a surgical mask and social distancing should be taken regardless of the patient Covid-19 status [10]; further peculiar precautions should be adopted in addition during critic procedures involving the respiratory mucosa, such as oro-tracheal aspiration, intubation, extubation, and/or when performing transnasal, transoral surgery, being essential to distinguish COVID-19-positive patients from the negative ones [6, 10, 11, 19].
T37 1572-1812 Sentence denotes Hence, in the last month, only three patients required urgent treatment, respectively, for the treatment of a pituitary apoplexy, a chondrosarcoma causing cavernous sinus syndrome and a pituitary macroadenoma determining chiasm compression.
T38 1813-1967 Sentence denotes Once we cleared COVID-19 status (telephone interview and serological exam were run), we decided to adopt endoscopic endonasal approach in all these cases.
T39 1969-1991 Sentence denotes Measures inside the OR
T40 1992-2241 Sentence denotes Only surgeons and nurses directly involved in the procedures have been admitted to the theater; it was mandatory for each of them to wear maximum level PPE [6, 11, 20, 21]: FFP2 mask, covered by surgical mask, disposable gowns and caps, face screen.
T41 2243-2266 Sentence denotes Technical consideration
T42 2267-2438 Sentence denotes Considering all the above, we retained useful to adopt peculiar surgical technique modifications, in order to further limit the spread of droplets and aerosols [3, 11, 24]
T43 2439-2603 Sentence denotes Before starting, cottonoid pledgets soaked with diluted iodopovidone are placed and left in place for at least 5 min to rinse off mucosa from any contamination [5];
T44 2604-2950 Sentence denotes After usual nasal pyramid sterile draping, an endonasal surgery facial mask, namely a nose lid, is assembled: a sterile non-latex glove layer is used to cover nostril and fixed with adhesive protection film over the nasal bridge; initially, two and then three narrow slit cut are placed over the nares to let instruments enter the nostrils (Figs.
T45 2951-2964 Sentence denotes 1, 2, and 3).
T46 2965-3083 Sentence denotes Fig. 1 Pictures showing the layer of sterile non-latex glove with a two and b three slit cuts, being used as nose lid.
T47 3084-3144 Sentence denotes Without any instrument that pierces it, the cuts are minimal
T48 3145-3195 Sentence denotes Fig. 2 Picture showing the intraoperative setting.
T49 3196-3643 Sentence denotes The nose lid is fixed with adhesive protection film over the nasal bridge and instruments can slide through the slit cuts the lid adheres to their outer diameter. a The endoscope is inserted through one nostril, i.e., the right. b Three-four hands technique: the endoscope is held by assistant at the most superior aspect of the left nostril and the surgeon holds the instruments inside the right nostril and the suction tube beneath the endoscope
T50 3644-4136 Sentence denotes Fig. 3 Picture showing the details of intraoperative setting demonstrating that air flow through the nose can be limited by the use of the nose lid. a The microdrill is inserted through the left nostril and the nose lid adheres to its outer diameter. b The endoscope and suction tube are inserted through one nostril, i.e., the right, in two different slit cuts. c The endoscope is inserted through the right nostril while the microdrill in the left one, each of them in the relative slit cut
T51 4137-4260 Sentence denotes The slit cuts permit to limit the empty space of the nares allowing the entrance and exit only of the surgical instruments.
T52 4261-4374 Sentence denotes The procedure then has been run as usual throughout into 3 steps: the nasal, the sphenoid, and the sellar phases.
T53 4375-4537 Sentence denotes A corridor between middle turbinates and the nasal septum is created and thereafter the nasal septum is detached from the sphenoid rostrum with blunt instruments.
T54 4538-4577 Sentence denotes Cautery is limited as much as possible.
T55 4578-4910 Sentence denotes The anterior wall of the sphenoid sinus is widely opened with osteotomes and rongeurs preferably and opening of the sellar floor is performed using chisel and hammer; microdrill with continuous irrigation, to reduce as much as possible the spreading of aerosol and bone dust, is used only to refine skull base opening upon the need.