| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T536 |
0-176 |
Sentence |
denotes |
Studies suggest that inhibiting EGFR signaling might prevent an excessive fibrotic response to SARS-CoV and other respiratory infections (like that characteristic of COVID-19). |
| T537 |
177-333 |
Sentence |
denotes |
EGFR plays a role in interstitial lung disease, and interaction between EGF and TFG-beta signaling is believed to drive development of fibrosis (116) (117). |
| T538 |
334-566 |
Sentence |
denotes |
The role of EGFR signaling in the development of lung fibrosis is complex, though, with data suggesting both profibrotic and antifibrotic roles for EGFR signaling, at least in part seeming to depend on the trigger for fibrosis (13). |
| T539 |
567-791 |
Sentence |
denotes |
Gefitinib inhibited TGF-beta1 induction of fibrosis in vivo (118) and inhibited bleomycin-induced fibrosis in a mouse model (119), and erlotinib was reported to block fibrosis development in a variety of in vivo models (13). |
