| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T507 |
0-82 |
Sentence |
denotes |
Kinase inhibitors as potential therapeutics for COVID-19 respiratory complications |
| T508 |
83-367 |
Sentence |
denotes |
Kinase inhibitors that have been approved for treatment of various malignancies have properties, such as anti-inflammatory and cytokine inhibitory activity, which may be able to reduce the likelihood of life-threatening conditions due to lung damage from respiratory virus infections. |
| T509 |
368-709 |
Sentence |
denotes |
Numerous small molecule kinase inhibitors target proteins associated with severe respiratory distress, including cytokines (such as IL-6 and TNF-alpha) that contribute to cytokine release syndrome and sHLH, as well as proteins associated with inflammation and induction of pulmonary fibrosis (such as the pro-inflammatory cytokine TGF-beta). |
