PMC:7417114 / 32503-33351 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T256 0-387 Sentence denotes Epidermal growth factor receptor (EGFR) has been implicated in infection by a wide range of unrelated viruses (50), including the spread and motility of vaccinia virus (51) and the processes of endocytosis (for influenza A and HCV), and entry and/or post-entry events (for human cytomegalovirus (HCMV) and adeno-associated virus serotype A (AAV6) (Table 1) (52) (53) (54) (55) (56) (57).
T257 388-585 Sentence denotes In fact, among the first studies to show that tyrosine kinase inhibitors can have significant antiviral activity was one identifying EGFR as a co-factor for entry of HCV into human host cells (56).
T258 586-701 Sentence denotes EGFR is also used by different viruses, including many respiratory viruses, to evade the host immune response (58).
T259 702-848 Sentence denotes Activity against HCMV and HCV in vitro and in vivo has been demonstrated by the EGFR-targeting inhibitors, gefitinib and erlotinib (59) (56) (57).