| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T82 |
0-368 |
Sentence |
denotes |
A number of approved antiviral treatments are designed to inhibit enzymes such as polymerases or proteases through a “one drug, one bug” line of attack, which has been deemed inadequate due to the inefficiency of these treatments in working against multiple viruses, as well as failure to treat emerging new strains with accumulating mutations that are drug-resistant. |
| T83 |
369-654 |
Sentence |
denotes |
The high cost and lengthy timeline for development of a novel agent are additional factors that dramatically limit the efficiency of this approach for covering a wide range of existing viruses as well as newly emerging ones or those that have developed resistance to current therapies. |
| T84 |
655-863 |
Sentence |
denotes |
A different strategy involves targeting integral host cell proteins that are required by a broad spectrum of pathogens, including those that are emerging and novel and for which no effective treatment exists. |
| T85 |
864-1002 |
Sentence |
denotes |
An advantage of targeting host cellular proteins is that they do not undergo the same mutation rates that are seen for genomes of viruses. |
