Id |
Subject |
Object |
Predicate |
Lexical cue |
T27 |
0-11 |
Sentence |
denotes |
Case report |
T28 |
12-210 |
Sentence |
denotes |
A 56-year-old Caucasian woman with a medical history of mild arterial hypertension (valsartan 40 mg) and hypothyreosis (l-thyroxin 25 µg) suffers from a dry cough, mild fever and a general weakness. |
T29 |
211-327 |
Sentence |
denotes |
In the context of the COVID-19 pandemic, SARS-CoV-2 RT-PCR on nasopharyngeal swab was performed and tested positive. |
T30 |
328-361 |
Sentence |
denotes |
A quarantine at home was decreed. |
T31 |
362-457 |
Sentence |
denotes |
The presumed contact to an infected person has been 12 days before the first symptoms appeared. |
T32 |
458-584 |
Sentence |
denotes |
Seven days later, she noticed weakness of her limbs while climbing stairs and a tingling sensation in all fingertips and toes. |
T33 |
585-689 |
Sentence |
denotes |
She was admitted to our emergency department 3 days after the occurrence of these neurological symptoms. |
T34 |
690-874 |
Sentence |
denotes |
On physical examination, the patient was afebrile with blood pressure at 135/82 mmHg, heart rate of 110 beats/min, respiratory rate at 18/min, and oxygen saturation of 95% on room air. |
T35 |
875-943 |
Sentence |
denotes |
She was conscious and had no dyspnea at the time of hospitalization. |
T36 |
944-1055 |
Sentence |
denotes |
The neurological examination showed no meningeal irritation signs or abnormalities in the cranial nerve status. |
T37 |
1056-1286 |
Sentence |
denotes |
The muscle strength examination showed paresis in four limbs with a Medical Research Council (MRC) scale of 4/5 in the proximal, 3/5 in the distal upper extremities, 4/5 in the proximal, and 3/5 in distal in the lower extremities. |
T38 |
1287-1385 |
Sentence |
denotes |
Deep tendon reflexes were generally absent and there were no signs of upper motor neuron disorder. |
T39 |
1386-1534 |
Sentence |
denotes |
There was a reduction in the vibration of the knees from 2/8 in the 128 Hz tuning fork test, and fine touch sensation was bilateral stocking shaped. |
T40 |
1535-1568 |
Sentence |
denotes |
There was no spine sensory level. |
T41 |
1569-1648 |
Sentence |
denotes |
Meningeal irritation signs and upper motor neuron disorder signs were negative. |
T42 |
1649-2036 |
Sentence |
denotes |
The laboratory results were as follows: white blood cell count 11,400 cells per microliter (neutrophils = 82.7%; lymphocytes = 10.4%), fibrinogen 4.93 g/l, C-reactive protein < 2 mg/l, hemoglobin 7.8 g/dL, serum glucose 5.79 mmol/l, and further normal results for blood urea nitrogen, creatinine, ALAT, ASAT, LDH, GGT, sodium, potassium, INR, PTT, IgG, IgA, IgM, and complete urinalysis. |
T43 |
2037-2101 |
Sentence |
denotes |
Anti-ganglioside antibodies (GM1-, GQ1b-antibodies) were absent. |
T44 |
2102-2295 |
Sentence |
denotes |
The analysis of cerebrospinal fluid (CSF) showed a cell count of 9 Mpt/l (lymphocytes and monocytes), protein of 0.575 g/l, glucose 3.74 mmol/l and lactate 2.2 mmol/l, and no oligoclonal bands. |
T45 |
2296-2359 |
Sentence |
denotes |
The SARS-CoV-2 RT-PCR in CSF was performed and tested negative. |
T46 |
2360-2518 |
Sentence |
denotes |
Biological tests were not in favor of a recent infection with Borrelia, Treponema pallidum, Campylobacter jejuni, mycoplasma, EBV, HSV1 or 2, and hepatitis E. |
T47 |
2519-2587 |
Sentence |
denotes |
A CT scan of the brain and MRI of the spine showed no abnormalities. |
T48 |
2588-2824 |
Sentence |
denotes |
Lung CT at admission showed leaky infiltrates in the right lower lobe, at the tip and dorsally; infiltrates most likely began in the dorsal left in the lower lobe, increased, with maximum 22 mm paratracheal and infracarinal lymph nodes. |
T49 |
2825-2944 |
Sentence |
denotes |
The patient was admitted to ICU and further treatment was carried out in strict compliance with the isolation measures. |
T50 |
2945-3074 |
Sentence |
denotes |
Our patient received PPh every 2 days, and there was a clinical deterioration in spite of this treatment during the first 5 days. |
T51 |
3075-3401 |
Sentence |
denotes |
The patient developed a flaccid, severe tetraparesis of 3/5 in the proximal, 1/5 in the distal of the upper extremities and 3/5 in the proximal and 0/5 in the distal of the lower extremities for dorsal extension, 2/5 for flexion, a trunk instability, and also bilateral peripheral facial nerve palsy (House–Brackmann grade 5). |
T52 |
3402-3566 |
Sentence |
denotes |
There were autonomous symptoms with a tachycardic heart action until 120/min and a severe orthostatic dysregulation, with no further possibility of sitting upright. |
T53 |
3567-3644 |
Sentence |
denotes |
She showed a tendency for clinical improvement after the third course of PPh. |
T54 |
3645-3681 |
Sentence |
denotes |
Seven courses of PPh were performed. |
T55 |
3682-3876 |
Sentence |
denotes |
The PPh caused a slightly further clinical improvement with asymmetrical improvement of facial paresis and tetraparesis, but a clinical stagnation of the improvement during the following 5 days. |
T56 |
3877-3977 |
Sentence |
denotes |
The patient was still unable to sit upright because of orthostatic collapsing and trunk instability. |
T57 |
3978-4092 |
Sentence |
denotes |
Therefore, we added 5 days after the last PPh 0.40 g/kg/day intravenous immune globulins for a duration of 5 days. |
T58 |
4093-4211 |
Sentence |
denotes |
We performed the neurophysiological study and nerve sonography only on day 10 according to the isolation requirements. |
T59 |
4212-4368 |
Sentence |
denotes |
Nerve sonography, as a painless technique for bedside-imaging nerve pathology, demonstrated a hypoechoic ultrasonographic cervical spinal nerve enlargement. |
T60 |
4369-4454 |
Sentence |
denotes |
The cross-sectional area of the C6 root was measured as 21 mm2 and C7 root as 22 mm2. |
T61 |
4455-4592 |
Sentence |
denotes |
Enlarged cervical spinal and peripheral nerves detected by ultrasound were identified as an early marker for Guillain–Barré syndrome [7]. |
T62 |
4593-4803 |
Sentence |
denotes |
Electroneurographic parameters demonstrate the typical delay of distal motor latency, and F-wave latency and decrease of conduction velocity, as well as decreased amplitudes at compound muscle action potential. |
T63 |
4804-4911 |
Sentence |
denotes |
There was mild decrease of conduction velocity of sensory nerve action potential changes at the arm nerves. |
T64 |
4912-5022 |
Sentence |
denotes |
The findings are basically consistent with acute motor accented and axonal demyelinating neuropathy (Table 1). |
T65 |
5023-5071 |
Sentence |
denotes |
Table 1 Nerve conduction study parameters day 10 |
T66 |
5072-5207 |
Sentence |
denotes |
Nerve stimulated Stimulation SITE Amplitude (m in mV; s in µV) Latency (ms) Conduction velocity (m/s) F-Wave (ms)/F-wavepersistence (%) |
T67 |
5208-5287 |
Sentence |
denotes |
Right Left Norm Right Left Norm Right Left Norm right left Norm (height 175 cm) |
T68 |
5288-5345 |
Sentence |
denotes |
Medianus (s) Wrist 8.9 17.2 ≥ 6 3.7 4.25 3.2 35 33 ≥ 44 |
T69 |
5346-5399 |
Sentence |
denotes |
Ulnaris (s) Wrist 10 31 ≥ 5 2.7 3.15 2.8 40 35 ≥ 44 |
T70 |
5400-5445 |
Sentence |
denotes |
Suralis (s) Calf 9 9 ≥ 5 2 2.1 2 49 50 ≥ 40 |
T71 |
5446-5521 |
Sentence |
denotes |
Medianus (m) Wrist 5 5.6 ≥ 3.5 6.6 6.2 ≤ 4.2 39.7/80 33.6/30 ≤ 31/50–100 |
T72 |
5522-5576 |
Sentence |
denotes |
Antecubital fossa 4.2 5.6 ≥ 3.5 12.1 10.9 44 45 ≥ 50 |
T73 |
5577-5641 |
Sentence |
denotes |
Ulnaris (m) Wrist 0.7 1.8 ≥ 2.8 4.6 4 ≤ 3.4 35 33 ≤ 31/50–100 |
T74 |
5642-5690 |
Sentence |
denotes |
Below elbow 1.2 0.7 ≥ 2.8 11 11.2 39 35.9 ≥ 48 |
T75 |
5691-5759 |
Sentence |
denotes |
Tibialis (m) Ankle 1.5 0.9 ≥ 2.9 4.9 7.9 ≤ 6 nr 73/20 ≤ 58/50–100 |
T76 |
5760-5812 |
Sentence |
denotes |
Popliteal fossa 0.5 0.3 ≥ 2.9 16.4 19.8 33 33 ≥ 41 |
T77 |
5813-5884 |
Sentence |
denotes |
Peroneus (m) Ankle 2.2 2.1 ≥ 2.5 3.5 5.1 ≤ 5 70/30 66/20 ≤ 57/50–100 |
T78 |
5885-5928 |
Sentence |
denotes |
Fibula 0.57 0.69 ≥ 2.5 14.1 15 30 33 ≥ 40 |
T79 |
5929-5943 |
Sentence |
denotes |
nr no response |
T80 |
5944-6003 |
Sentence |
denotes |
There was no fever or respiratory complaints over the time. |
T81 |
6004-6135 |
Sentence |
denotes |
Further treatment was given in the intermediate care unit, but there was only a slight clinical improvement over the next few days. |
T82 |
6136-6370 |
Sentence |
denotes |
The clinical course up to the time of transfer to a rehabilitation facility and the eletroneurographic findings with evidence of an axonal motor damage can indicate a complicated course with a prolonged and possible defective healing. |