Id |
Subject |
Object |
Predicate |
Lexical cue |
T672 |
0-184 |
Sentence |
denotes |
The heterologous immune effects induced by Bacillus Calmette Guérin (BCG) vaccination is a promising strategy for controlling the COVID-19 pandemic and requires further investigations. |
T673 |
185-256 |
Sentence |
denotes |
BCG is a widely used vaccine against tuberculosis in high-risk regions. |
T674 |
257-324 |
Sentence |
denotes |
It is derived from a live attenuated strain of Mycobacterium bovis. |
T675 |
325-460 |
Sentence |
denotes |
At present, three new clinical trials have been registered to evaluate the protective role of BCG vaccination against SARS-CoV-2 (363). |
T676 |
461-585 |
Sentence |
denotes |
Recently, a cohort study was conducted to evaluate the impact of childhood BCG vaccination in COVID-19 PCR positivity rates. |
T677 |
586-743 |
Sentence |
denotes |
However, childhood BCG vaccination was found to be associated with a rate of COVID-19-positive test results similar to that of the nonvaccinated group (364). |
T678 |
744-881 |
Sentence |
denotes |
Further studies are required to analyze whether BCG vaccination in childhood can induce protective effects against COVID-19 in adulthood. |
T679 |
882-1013 |
Sentence |
denotes |
Population genetic studies conducted on 103 genomes identified that the SARS-CoV-2 virus has evolved into two major types, L and S. |
T680 |
1014-1123 |
Sentence |
denotes |
Among the two types, L type is expected to be the most prevalent (∼70%), followed by the S type (∼30%) (366). |
T681 |
1124-1285 |
Sentence |
denotes |
This finding has a significant impact on our race to develop an ideal vaccine, since the vaccine candidate has to target both strains to be considered effective. |
T682 |
1286-1402 |
Sentence |
denotes |
At present, the genetic differences between the L and S types are very small and may not affect the immune response. |
T683 |
1403-1526 |
Sentence |
denotes |
However, we can expect further genetic variations in the coming days that could lead to the emergence of new strains (367). |