PMC:7405836 / 94503-96078 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE-old TextAE

Id Subject Object Predicate Lexical cue
T657 0-128 Sentence denotes Scientists from all over the world are trying hard to develop working vaccines with robust protective immunity against COVID-19.
T658 129-506 Sentence denotes Vaccine candidates, like mRNA-1273 SARS-CoV-2 vaccine, INO-4800 DNA coronavirus vaccine, and adenovirus type 5 vector vaccine candidate (Ad5-nCoV), are a few examples under phase I clinical trials, while self-amplifying RNA vaccine, oral recombinant COVID-19 vaccine, BNT162, plant-based COVID-19 vaccine, and Ii-Key peptide COVID-19 vaccine are under preclinical trials (297).
T659 507-638 Sentence denotes Similarly, the WHO, on its official website, has mentioned a detailed list of COVID-19 vaccine agents that are under consideration.
T660 639-932 Sentence denotes Different phases of trials are ongoing for live attenuated virus vaccines, formaldehyde alum inactivated vaccine, adenovirus type 5 vector vaccine, LNP-encapsulated mRNA vaccine, DNA plasmid vaccine, and S protein, S-trimer, and Ii-Key peptide as a subunit protein vaccine, among others (298).
T661 933-1123 Sentence denotes The process of vaccine development usually takes approximately ten years, in the case of inactivated or live attenuated vaccines, since it involves the generation of long-term efficacy data.
T662 1124-1219 Sentence denotes However, this was brought down to 5 years during the Ebola emergency for viral vector vaccines.
T663 1220-1325 Sentence denotes In the urgency associated with the COVID-19 outbreaks, we expect a vaccine by the end of this year (343).
T664 1326-1575 Sentence denotes The development of an effective vaccine against COVID-19 with high speed and precision is the combined result of advancements in computational biology, gene synthesis, protein engineering, and the invention of advanced manufacturing platforms (342).