Id |
Subject |
Object |
Predicate |
Lexical cue |
T628 |
0-118 |
Sentence |
denotes |
Multiepitope subunit vaccines can be considered a promising preventive strategy against the ongoing COVID-19 pandemic. |
T629 |
119-218 |
Sentence |
denotes |
In silico and advanced immunoinformatic tools can be used to develop multiepitope subunit vaccines. |
T630 |
219-395 |
Sentence |
denotes |
The vaccines that are engineered by this technique can be further evaluated using docking studies and, if found effective, then can be further evaluated in animal models (365). |
T631 |
396-535 |
Sentence |
denotes |
Identifying epitopes that have the potential to become a vaccine candidate is critical to developing an effective vaccine against COVID-19. |
T632 |
536-699 |
Sentence |
denotes |
The immunoinformatics approach has been used for recognizing essential epitopes of cytotoxic T lymphocytes and B cells from the surface glycoprotein of SARS-CoV-2. |
T633 |
700-787 |
Sentence |
denotes |
Recently, a few epitopes have been recognized from the SARS-CoV-2 surface glycoprotein. |
T634 |
788-959 |
Sentence |
denotes |
The selected epitopes explored targeting molecular dynamic simulations, evaluating their interaction with corresponding major histocompatibility complex class I molecules. |
T635 |
960-1007 |
Sentence |
denotes |
They potentially induce immune responses (176). |
T636 |
1008-1093 |
Sentence |
denotes |
The recombinant vaccine can be designed by using rabies virus (RV) as a viral vector. |
T637 |
1094-1210 |
Sentence |
denotes |
RV can be made to express MERS-CoV S1 protein on its surface so that an immune response is induced against MERS-CoV. |
T638 |
1211-1415 |
Sentence |
denotes |
The RV vector-based vaccines against MERS-CoV can induce faster antibody response as well as higher degrees of cellular immunity than the Gram-positive enhancer matrix (GEM) particle vector-based vaccine. |
T639 |
1416-1498 |
Sentence |
denotes |
However, the latter can induce a very high antibody response at lower doses (167). |
T640 |
1499-1613 |
Sentence |
denotes |
Hence, the degree of humoral and cellular immune responses produced by such vaccines depends upon the vector used. |